Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

Description

This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.

Conditions

Psychosis, Prodromal Schizophrenia, Prodromal Symptoms

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Study Overview

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Study Details

Study overview

This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk in Adolescents at Clinical High Risk for Psychosis

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

Condition
Psychosis
Intervention / Treatment

-

Contacts and Locations

Glen Oaks

Northwell Health- The Zucker Hillside Hospital, Glen Oaks, New York, United States, 11042

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level
  • * A score representing 0.5 SD below the mean on Animal Naming, Trails A or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB).
  • * Any DSM 5 Schizophrenia-Spectrum diagnosis
  • * Non-English speaking
  • * Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder)
  • * Estimated IQ\<70
  • * Significant head injury
  • * Significant substance abuse
  • * Significant visual or auditory impairment.

Ages Eligible for Study

14 Years to 20 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Northwell Health,

Barbara A Cornblatt, Ph.D., PRINCIPAL_INVESTIGATOR, Northwell Health

Study Record Dates

2026-05-31