ACTIVE_NOT_RECRUITING

AN/BN Risk Factors Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Across the United States, thousands of children and adolescents suffer from eating disorders. Among young women alone, an estimated 2 to 4 percent are dealing with anorexia nervosa. Anorexia nervosa also has the highest mortality rate of any psychiatric disorder and produces a six-fold increased risk for death. Unfortunately, study shows that current treatments are only successful with 25 percent of patients and no eating disorder prevention program has been found to reduce future onset of anorexia nervosa. The goal of this study is to conduct a highly innovative pilot study that will identify risk factors that predict future onset of anorexia nervosa and investigate how the risk processes for anorexia nervosa are different from the risk processes for bulimia nervosa. The proposed pilot study will: * Compare 30 healthy adolescent girls at high risk for anorexia nervosa to 30 healthy adolescent girls at high risk for bulimia nervosa, and 30 healthy adolescent girls at low risk for eating disorder in an effort to document risk processes that are present in early adolescence before anorexia nervosa typically emerges. * Test whether elevations in the hypothesized risk factors predict future onset of anorexia nervosa over a four-year follow-up.

Official Title

Identifying Risk Factors That Predict Onset of Anorexia Nervosa and Bulimia Nervosa

Quick Facts

Study Start:2021-11-23
Study Completion:2029-05-26
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05133037

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:12 Years to 16 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Female
  2. * Ages 12 - 16
  3. * Must have biological parental history of AN or BN, or no history of psychiatric diagnoses
  1. * Current diagnosis of an Eating Disorder;
  2. * Symptoms of major psychiatric disorders (substance use disorders, conduct disorder, attention deficit hyperactive disorder, major depression, bipolar disorder, panic disorder, agoraphobia, generalized anxiety disorder);
  3. * Serious medical conditions (diabetes, brain injury, cancer);
  4. * Body Mass Index (BMI) \<17.5;
  5. * Any contraindications for MRI (e.g. metal objects/implants in body, irremovable body piercings, tattoos or braces, medications that interfere with MRI, history of head injury with loss of consciousness, phobia that wouldn't allow them to complete the MRI);
  6. * Current regular psychoactive drug use;
  7. * Relevant food allergies;
  8. * Not in age range

Contacts and Locations

Principal Investigator

Eric Stice, PhD
PRINCIPAL_INVESTIGATOR
Stanford University

Study Locations (Sites)

Stanford University
Stanford, California, 94305
United States

Collaborators and Investigators

Sponsor: Stanford University

  • Eric Stice, PhD, PRINCIPAL_INVESTIGATOR, Stanford University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-11-23
Study Completion Date2029-05-26

Study Record Updates

Study Start Date2021-11-23
Study Completion Date2029-05-26

Terms related to this study

Additional Relevant MeSH Terms

  • Eating Disorders