The goal of the study is to generate a biorepository of longitudinal biofluids-blood (plasma and serum), cerebral spinal fluid (CSF) and urine linked to genetics and longitudinal clinical information that are made available to the research community. To accomplish these goals, we will enroll 800 Amyotrophic Lateral Sclerosis (ALS) patients and 200 healthy controls from sites globally, over a 5 year time frame. Additionally, speech and motor function and spirometry measures will be collected bi-weekly in a subset of participants. ALS participants will be asked to come to the clinic for 5 study visits approximately every 4 months. Healthy participants will be coming for 2 study visits with a 12-month interval between visits. These samples and clinical information will be stored in a de-identified manner and made available for investigators to use in future research studies.
Amyotrophic Lateral Sclerosis, Movement Disorders, Degenerative Disorder, Motor Neuron Disease
The goal of the study is to generate a biorepository of longitudinal biofluids-blood (plasma and serum), cerebral spinal fluid (CSF) and urine linked to genetics and longitudinal clinical information that are made available to the research community. To accomplish these goals, we will enroll 800 Amyotrophic Lateral Sclerosis (ALS) patients and 200 healthy controls from sites globally, over a 5 year time frame. Additionally, speech and motor function and spirometry measures will be collected bi-weekly in a subset of participants. ALS participants will be asked to come to the clinic for 5 study visits approximately every 4 months. Healthy participants will be coming for 2 study visits with a 12-month interval between visits. These samples and clinical information will be stored in a de-identified manner and made available for investigators to use in future research studies.
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
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Barrow Neurological Institute, Phoenix, Arizona, United States, 85013
University of California San Diego, San Diego, California, United States, 92121
Georgetown University, Georgetown, District of Columbia, United States, 20007
Mayo Clinic, Jacksonville, Florida, United States, 32224
Northwestern University, Chicago, Illinois, United States, 60611
Massachusetts General Hospital, Boston, Massachusetts, United States, 02114
Washington University, Saint Louis, Missouri, United States, 63110
Columbia University, New York, New York, United States, 10032
Baylor College of Medicine, Houston, Texas, United States, 77030
University of Washington, Seattle, Washington, United States, 98195
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
Yes
Target ALS Foundation, Inc.,
Laura Dugom, MPH, STUDY_DIRECTOR, Target ALS Foundation, Inc.
Amy Easton, PhD, STUDY_DIRECTOR, Target ALS Foundation, Inc.
2031-12-31