RECRUITING

Conservative Management for PAS Pilot

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Conservative in situ management is a promising alternative treatment to hysterectomy for patients with placenta accreta spectrum and may be safer and preferable for some patients. This study will assess feasibility of a future randomized clinical trial comparing these treatments and provide novel data to inform shared decision-making and cost-effective care for patients with this deadly pregnancy disorder.

Official Title

Conservative Management as an Alternative to Hysterectomy for Placenta Accreta Spectrum: a Pilot Randomized Controlled Trial.

Quick Facts

Study Start:2022-05-26
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05139498

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 99 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18 and older
  2. * History of cesarean delivery AND placenta previa OR anterior low-lying placenta AND suspected of having PAS on prenatal imaging (ultrasound/MRI)
  3. * Patients who would typically be recommended for hysterectomy
  4. * Planned delivery between 34w0d and 36w0d gestation.
  1. * Plan to delivery before neonatal viability (\<24 weeks gestation)
  2. * Hospitalized for antenatal hemorrhage
  3. * Have a low antenatal suspicion for PAS based on imaging
  4. * Are pregnant with multiples (twins, triplets)
  5. * Have a uterine fetal demise

Contacts and Locations

Study Contact

Ashley Joseph
CONTACT
801-903-3278
ashley.joseph@hsc.utah.edu
Marie Gibson
CONTACT
801-213-2845
marie.gibson@hsc.utah.edu

Principal Investigator

Brett Einerson, MD
PRINCIPAL_INVESTIGATOR
University of Utah

Study Locations (Sites)

University of Utah
Salt Lake City, Utah, 84132
United States

Collaborators and Investigators

Sponsor: University of Utah

  • Brett Einerson, MD, PRINCIPAL_INVESTIGATOR, University of Utah

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-05-26
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2022-05-26
Study Completion Date2026-06-30

Terms related to this study

Keywords Provided by Researchers

  • Pregnancy

Additional Relevant MeSH Terms

  • Placenta Accreta