Conservative Management for PAS Pilot

Description

Conservative in situ management is a promising alternative treatment to hysterectomy for patients with placenta accreta spectrum and may be safer and preferable for some patients. This study will assess feasibility of a future randomized clinical trial comparing these treatments and provide novel data to inform shared decision-making and cost-effective care for patients with this deadly pregnancy disorder.

Conditions

Placenta Accreta

Study Overview

Study Details

Study overview

Conservative in situ management is a promising alternative treatment to hysterectomy for patients with placenta accreta spectrum and may be safer and preferable for some patients. This study will assess feasibility of a future randomized clinical trial comparing these treatments and provide novel data to inform shared decision-making and cost-effective care for patients with this deadly pregnancy disorder.

Conservative Management as an Alternative to Hysterectomy for Placenta Accreta Spectrum: a Pilot Randomized Controlled Trial.

Conservative Management for PAS Pilot

Condition
Placenta Accreta
Intervention / Treatment

-

Contacts and Locations

Salt Lake City

University of Utah, Salt Lake City, Utah, United States, 84132

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18 and older
  • * History of cesarean delivery AND placenta previa OR anterior low-lying placenta AND suspected of having PAS on prenatal imaging (ultrasound/MRI)
  • * Patients who would typically be recommended for hysterectomy
  • * Planned delivery between 34w0d and 36w0d gestation.
  • * Plan to delivery before neonatal viability (\<24 weeks gestation)
  • * Hospitalized for antenatal hemorrhage
  • * Have a low antenatal suspicion for PAS based on imaging
  • * Are pregnant with multiples (twins, triplets)
  • * Have a uterine fetal demise

Ages Eligible for Study

18 Years to 99 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Utah,

Brett Einerson, MD, PRINCIPAL_INVESTIGATOR, University of Utah

Study Record Dates

2026-06-30