ACTIVE_NOT_RECRUITING

Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is particularly scarce. Therefore, we designed a prospective, randomized trial comparing the postoperative pain control in minimally invasive ventral and inguinal hernia repair patients who receive an Exaparel-based TAP block compared to the traditional bupivacaine (Marcaine) TAP block.

Official Title

The Evaluation of Post-operative Pain Control With a TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Quick Facts

Study Start:2022-03-01
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05177991

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years of age or older
  2. * Have a ventral or inguinal hernia requiring surgical repair
  1. * Less than 18 years of age
  2. * Chronic pain patients
  3. * Having a defect \>10 cm in transverse dimension
  4. * Having a defect \<4 cm
  5. * Has an allergy to bupivacaine
  6. * Has recurrent hernias as per medical history
  7. * A TAP block performed at any time aside from just prior to the start of the procedure
  8. * If bupivacaine is mixed with other anesthetics
  9. * Under the instance of an emergency surgery (trauma)
  10. * Concomitant surgery
  11. * History of EtOH abuse
  12. * History of liver/kidney dysfunction
  13. * If the procedure must be converted to open
  14. * Inidividual's weight \< 50kg
  15. * Individual's BMI \> 45

Contacts and Locations

Principal Investigator

Leslie Son, PhD
STUDY_DIRECTOR
Our Lady of the Lake Hospital

Study Locations (Sites)

Karl LeBlanc
Baton Rouge, Louisiana, 70808
United States

Collaborators and Investigators

Sponsor: Leslie Son

  • Leslie Son, PhD, STUDY_DIRECTOR, Our Lady of the Lake Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-03-01
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2022-03-01
Study Completion Date2025-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Inguinal Hernia
  • Ventral Hernia