Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Description

While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is particularly scarce. Therefore, we designed a prospective, randomized trial comparing the postoperative pain control in minimally invasive ventral and inguinal hernia repair patients who receive an Exaparel-based TAP block compared to the traditional bupivacaine (Marcaine) TAP block.

Conditions

Inguinal Hernia, Ventral Hernia

Study Overview

Study Details

Study overview

While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is particularly scarce. Therefore, we designed a prospective, randomized trial comparing the postoperative pain control in minimally invasive ventral and inguinal hernia repair patients who receive an Exaparel-based TAP block compared to the traditional bupivacaine (Marcaine) TAP block.

The Evaluation of Post-operative Pain Control With a TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Condition
Inguinal Hernia
Intervention / Treatment

-

Contacts and Locations

Baton Rouge

Karl LeBlanc, Baton Rouge, Louisiana, United States, 70808

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18 years of age or older
  • * Have a ventral or inguinal hernia requiring surgical repair
  • * Less than 18 years of age
  • * Chronic pain patients
  • * Having a defect \>10 cm in transverse dimension
  • * Having a defect \<4 cm
  • * Has an allergy to bupivacaine
  • * Has recurrent hernias as per medical history
  • * A TAP block performed at any time aside from just prior to the start of the procedure
  • * If bupivacaine is mixed with other anesthetics
  • * Under the instance of an emergency surgery (trauma)
  • * Concomitant surgery
  • * History of EtOH abuse
  • * History of liver/kidney dysfunction
  • * If the procedure must be converted to open
  • * Inidividual's weight \< 50kg
  • * Individual's BMI \> 45

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Leslie Son,

Leslie Son, PhD, STUDY_DIRECTOR, Our Lady of the Lake Hospital

Study Record Dates

2024-12-31