RECRUITING

Non-invasive Brain Mapping of Movement Facilitation in Parkinson's Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Several strategies or contexts help patients with Parkinson's disease to move more quickly or normally, however the brain mechanisms underlying these phenomena are poorly understood. The proposed studies use complimentary brain mapping techniques to understand the brain mechanisms supporting improved movements elicited by external cues. The central hypothesis is that distinct networks are involved in movement improvement depending on characteristics of the facilitating stimulus. Participants will perform movement tasks during recording of brain activity with EEG and MRI. The identified biomarkers may provide targets for future neuromodulation therapies to improve symptoms that are refractory to current treatments, such as freezing of gait.

Official Title

Non-invasive Brain Mapping of Movement Facilitation in Parkinson's Disease

Quick Facts

Study Start:2022-07-06
Study Completion:2026-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05179187

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of Parkinson's disease based on presence of at least 2 cardinal features (tremor, rigidity or bradykinesia) OR healthy adult with no neurologic disease
  2. * Age \> 18 years old
  1. * Dementia as indicated by score on Montreal Cognitive Assessment \< 19
  2. * Active hallucinations or psychosis
  3. * Contraindications to MRI (metal implant, claustrophobia)

Contacts and Locations

Study Contact

Katy Cross, MD, PhD
CONTACT
310-206-2828
kcross@mednet.ucla.edu
Ipek Talu, BA
CONTACT
310-206-2828
italu@mednet.ucla.edu

Study Locations (Sites)

University of California Los Angeles
Los Angeles, California, 90095
United States

Collaborators and Investigators

Sponsor: University of California, Los Angeles

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-07-06
Study Completion Date2026-09

Study Record Updates

Study Start Date2022-07-06
Study Completion Date2026-09

Terms related to this study

Keywords Provided by Researchers

  • movement
  • external cueing
  • brain mapping

Additional Relevant MeSH Terms

  • Parkinson Disease