A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin \[GO\]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who are unable to receive additional anthracyclines, or in 2nd relapse.
Acute Myeloid Leukemia
A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin \[GO\]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who are unable to receive additional anthracyclines, or in 2nd relapse.
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
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Phoenix Children's Hospital, Phoenix, Arizona, United States, 85016
Arkansas Children's Hospital, Little Rock, Arkansas, United States, 72202
MemorialCare Miller Children's and Women's Hospital Long Beach, Long Beach, California, United States, 90806
Children's Hospital of Orange County Main Campus - Orange, Orange, California, United States, 92868
Benioff Children's Hospital - Mission Bay, San Francisco, California, United States, 94158
Children's Hospital Colorado, Aurora, Colorado, United States, 80045
Yale University, New Haven, Connecticut, United States, 06511
Nemours Alfred I. Dupont Hospital for Children, Wilmington, Delaware, United States, 19803
Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida, United States, 33908
Nemours Children's Specialty Care Jacksonville, Jacksonville, Florida, United States, 32207
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
29 Days to 21 Years
ALL
No
LLS PedAL Initiative, LLC,
Seth Karol, MD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital
Marlous Bakker, STUDY_DIRECTOR, Princess Maxima Center for Pediatric Oncology
2032-02