Project HOME: Home-Based Treatment Options and Mechanisms for Eating Disorders

Description

This randomized, controlled effectiveness trial will assess outcomes, implementation, and mechanisms of two psychological treatments for adolescent anorexia nervosa (AN) delivered in the home setting, in the context of community-based mental health. Adolescents with AN-spectrum disorders (n=50) and their caregivers will be randomly assigned to either family-based treatment or integrated family therapy delivered in the home. Caregivers and adolescents will provide data on weight, eating, and putative treatment mechanisms, including caregiver self-efficacy, adolescent distress, and generalizability of treatment skills. Treatment feasibility, acceptability, and appropriateness will be measured among providers and participating families. The proposed study has clear potential to advance scientific and clinical understanding of the real-world effectiveness of psychological treatments for AN, including whether adapting them for the home setting may improve accessibility and effects on treatment outcome

Conditions

Anorexia Nervosa, Eating Disorders

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Study Overview

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Study Details

Study overview

This randomized, controlled effectiveness trial will assess outcomes, implementation, and mechanisms of two psychological treatments for adolescent anorexia nervosa (AN) delivered in the home setting, in the context of community-based mental health. Adolescents with AN-spectrum disorders (n=50) and their caregivers will be randomly assigned to either family-based treatment or integrated family therapy delivered in the home. Caregivers and adolescents will provide data on weight, eating, and putative treatment mechanisms, including caregiver self-efficacy, adolescent distress, and generalizability of treatment skills. Treatment feasibility, acceptability, and appropriateness will be measured among providers and participating families. The proposed study has clear potential to advance scientific and clinical understanding of the real-world effectiveness of psychological treatments for AN, including whether adapting them for the home setting may improve accessibility and effects on treatment outcome

Project HOME: Home-Based Treatment Options and Mechanisms for Eating Disorders

Project HOME: Home-Based Treatment Options and Mechanisms for Eating Disorders

Condition
Anorexia Nervosa
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 15213

Pawtucket

Gateway Healthcare, Pawtucket, Rhode Island, United States, 02860

Providence

The Providence Center, Providence, Rhode Island, United States, 02906

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Meets criteria for AN or atypical AN according to DSM-5 diagnostic criteria.
  • * Currently living at home with caregivers who are willing to engage in family treatment.
  • * Medically stable for outpatient treatment according to the recommended thresholds of the American Academy of Pediatrics and the Society of Adolescent Medicine (e.g., ≥75% of expected body weight, heartrate ≥50 beats per minute) and receiving medical monitoring from a clinician throughout treatment.
  • * If on psychotropic medication, meets all eligibility criteria while on stable dose of psychotropic medication for a co-morbid condition.
  • * Available for follow-up.
  • * Associated physical illness that necessitates hospitalization.
  • * Psychotic illness/other mental illness requiring hospitalization.
  • * Current dependence on drugs or alcohol.
  • * Physical conditions (e.g. diabetes mellitus, pregnancy) known to influence eating or weight.
  • * Concurrent involvement in other psychological treatment for an eating disorder.
  • * Developmental delay that would preclude participation in the intervention.

Ages Eligible for Study

12 Years to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Pittsburgh,

Andrea B Goldschmidt, Ph.D., PRINCIPAL_INVESTIGATOR, The University of Pittsburgh

Study Record Dates

2025-04-30