RECRUITING

Sleep and Circadian Mechanisms in Hypertension

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Conditions

HypertensionCardiovascular DiseasesCardiovascular Risk FactorsCircadian RhythmsSleepcardiovascularblood pressureconstant routinemicroneurographysleep regularization

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is a mechanistic clinical trial designed to investigate the effects of the circadian system and sleep on non-dipping blood pressure (BP) in people with hypertension (HTN).

Official Title

Sleep and Circadian Mechanisms in Hypertension

Quick Facts

Study Start:2022-08-04
Study Completion:2028-03-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05184933

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:25 Years to 64 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ages 25-64
  2. * BMI 18.5-42kg/m2
  3. * Hypertension (average resting blood pressure between 130/80 mmHg and 160/100 mmHg)
  1. * Over 5 pack-years of smoking;
  2. * Prior shift work within 12 months prior to the study;
  3. * Travel greater than three time zones for at least 3 months;
  4. * History of heart failure, cardiomyopathy, or history of bypass surgery, angioplasty, or previous myocardial infarction;
  5. * Acute or chronic diseases (except hypertension) that may affect outcome measures;
  6. * History of psychological conditions;
  7. * Sleep disorders, like severe sleep apnea, insomnia, etc.;
  8. * Prescription medications (Contraceptives and anti-hypertensive medications are permissible);
  9. * History of Illicit drug use and alcohol dependency;
  10. * 30 days free of cannabis use prior to the study;
  11. * Pregnancy;
  12. * Upper cut-off of 160/100 mmHg for BP

Contacts and Locations

Study Contact

Nicole Chaudhary, MPH
CONTACT
5034945536
clinphys@ohsu.edu

Principal Investigator

Saurabh S Thosar, PhD
PRINCIPAL_INVESTIGATOR
Oregon Health and Science University

Study Locations (Sites)

Oregon Health and Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Oregon Health and Science University

  • Saurabh S Thosar, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-08-04
Study Completion Date2028-03-30

Study Record Updates

Study Start Date2022-08-04
Study Completion Date2028-03-30

Terms related to this study

Keywords Provided by Researchers

  • cardiovascular
  • circadian rhythms
  • sleep
  • blood pressure
  • constant routine
  • microneurography
  • hypertension
  • sleep regularization

Additional Relevant MeSH Terms

  • Hypertension
  • Cardiovascular Diseases
  • Cardiovascular Risk Factors
  • Circadian Rhythms
  • Sleep