Healthy Living After Knee Replacement

Description

The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to a chronic disease self-management program.

Conditions

Arthroplasty, Overweight and Obesity

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Study Overview

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Study Details

Study overview

The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to a chronic disease self-management program.

Physical Activity and Weight Loss to Improve Function and Pain After Total Knee Replacement

Healthy Living After Knee Replacement

Condition
Arthroplasty
Intervention / Treatment

-

Contacts and Locations

Columbia

University of South Carolina, Columbia, South Carolina, United States, 29208

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * have a body mass index between 25-45 kg/m2
  • * have had a knee replacement (including primary, staged or independent bilateral, or revision) \<6 months prior to baseline assessment
  • * have a computer, tablet, or smartphone with active internet access to self-monitor online and/or have a device or computer compatible with Fitbit
  • * completion of baseline assessment measures (height, weight, function tests, surveys, ≥4 days valid of activity monitoring, and 1 day of dietary recall)
  • * be English-speaking and able to read consent and study materials written in English
  • * be willing to attend 4 in-person assessments.
  • * have any contraindications to diet or weight loss
  • * undergo simultaneous bilateral knee replacement or have a scheduled or anticipated knee replacement for the contralateral knee within the next 18 months
  • * have a mobility limiting comorbidity unrelated to knee replacement (e.g. spinal stenosis, fibromyalgia, peripheral vascular disease, stroke)
  • * are taking anti-obesity medications
  • * are enrolled in a formal weight loss program
  • * had or are planning to have bariatric/gastric/lap band surgery
  • * are planning to relocate out of the Columbia or Greenville, SC areas in the next 18 months.

Ages Eligible for Study

to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of South Carolina,

Christine Pellegrini, PhD, PRINCIPAL_INVESTIGATOR, University of South Carolina

Study Record Dates

2026-06-30