Metabolic Diet for Relapse Prevention in Anorexia Nervosa

Description

This is an interventional study that will test the safety, tolerability, and efficacy of the Metabolic Diet, which was designed as a treatment for women with anorexia nervosa to remain weight-stable after they have been restored from low weight. Participants will be adult women with anorexia nervosa who have been recently restored to normal weight and adult women with no history of eating disorders. After enrollment, participants will start meeting weekly with a registered dietitian to implement the Metabolic Diet in their daily lives, and will receive medical monitoring for adherence, side effects, changes in metabolic or psychological parameters, and weight stability.

Conditions

Anorexia Nervosa

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Study Overview

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Study Details

Study overview

This is an interventional study that will test the safety, tolerability, and efficacy of the Metabolic Diet, which was designed as a treatment for women with anorexia nervosa to remain weight-stable after they have been restored from low weight. Participants will be adult women with anorexia nervosa who have been recently restored to normal weight and adult women with no history of eating disorders. After enrollment, participants will start meeting weekly with a registered dietitian to implement the Metabolic Diet in their daily lives, and will receive medical monitoring for adherence, side effects, changes in metabolic or psychological parameters, and weight stability.

Metabolic Diet for Relapse Prevention in Anorexia Nervosa

Metabolic Diet for Relapse Prevention in Anorexia Nervosa

Condition
Anorexia Nervosa
Intervention / Treatment

-

Contacts and Locations

New York

Icahn School of Medicine at Mount Sinai, New York, New York, United States, 10029

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Female
  • * Age at least 18 and not over 40
  • * BMI at or above 18.5 kg/m2
  • * Speaks English
  • * Medically stable, as cleared by a licensed physician, with vital signs and initial blood draws
  • * History of DSM-5 diagnosis of Anorexia Nervosa (WR-AN only)
  • * Weight-restored from underweight BMI (under 18.5 kg/m2) within the past 6 months (WR-AN only)
  • * Current/lifetime diagnosis of DSM-5 psychotic disorders, bipolar disorders
  • * Active DSM-5 substance use disorders
  • * On medications that could affect metabolism
  • * History of suicide attempt within previous 6 months or acute suicide risk
  • * Significant current medical illness or metabolic conditions, including diabetes mellitus and pregnancy
  • * Current/lifetime diagnosis of DSM-5 eating disorders (HC only)
  • * Active DSM-5 depressive disorders (HC only)

Ages Eligible for Study

18 Years to 40 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Icahn School of Medicine at Mount Sinai,

Chinara Tate, PRINCIPAL_INVESTIGATOR, Icahn School of Medicine at Mount Sinai

Study Record Dates

2024-12