The purpose of this clinical trial (called the FLOTILLA study) is to give continued access to the study medicines, as well as safety follow-up, for participants in prior clinical trials of encorafenib and/or binimetinib. All participants who took part in earlier encorafenib and/or binimetinib studies may participate the FLOTILLA study if they are still benefiting from the use of the study medicines. This will be determined by the study doctor. People may not participate in the FLOTILLA study if they have not enrolled in a prior study of encorafenib or binimetinib. Participants that had enrolled but had stopped receiving the study treatment in a prior study cannot enrolled in this study. Participants in the FLOTILLA study will receive encorafenib and/or binimetinib at the same dose and frequency as in their prior study, for up to about 5 years.
Solid Tumors
The purpose of this clinical trial (called the FLOTILLA study) is to give continued access to the study medicines, as well as safety follow-up, for participants in prior clinical trials of encorafenib and/or binimetinib. All participants who took part in earlier encorafenib and/or binimetinib studies may participate the FLOTILLA study if they are still benefiting from the use of the study medicines. This will be determined by the study doctor. People may not participate in the FLOTILLA study if they have not enrolled in a prior study of encorafenib or binimetinib. Participants that had enrolled but had stopped receiving the study treatment in a prior study cannot enrolled in this study. Participants in the FLOTILLA study will receive encorafenib and/or binimetinib at the same dose and frequency as in their prior study, for up to about 5 years.
The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
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St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States, 85004
St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States, 85013
Massachusetts General Hospital, Boston, Massachusetts, United States, 02114
HealthPartners Cancer Research Center, Saint Paul, Minnesota, United States, 55101
Regions Hospital Pharmacy, Saint Paul, Minnesota, United States, 55101
HealthPartners Specialty Center, Saint Paul, Minnesota, United States, 55130
MSK Basking Ridge, Basking Ridge, New Jersey, United States, 07920
Rockefeller Outpatient Pavilion (53rd Street), New York, New York, United States, 10022
Memorial Sloan Kettering Cancer Center, New York, New York, United States, 10065
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
No
Pfizer,
Pfizer CT.gov Call Center, STUDY_DIRECTOR, Pfizer
2026-12-31