ACTIVE_NOT_RECRUITING

REFLECTION: A Clinical Practice Learning Program for Galleri®

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

REFLECTION is a multi-center, prospective, non-interventional, cohort study that will enroll approximately 14,000 individuals who have opted to be screened with Galleri®, a blood-based, multi-cancer early detection (MCED) test in routine clinical settings. The purpose of the study is to understand the real-world experience of Galleri® in clinical settings.

Official Title

REFLECTION: Real World Evidence for Learnings in Early Cancer Detection, a Clinical Practice Learning Program for Galleri®

Quick Facts

Study Start:2021-08-23
Study Completion:2026-10-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05205967

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:22 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participant has the ability to understand and the willingness to sign a written informed consent form (ICF);
  2. * Participant is at least 22 years old at the time of consent;
  3. * A provider or their designee has ordered the Galleri® test; and
  4. * Participant has the ability to comprehend the participant questionnaires.
  1. * There are no exclusions

Contacts and Locations

Study Locations (Sites)

Vincere Cancer Center
Scottsdale, Arizona, 85260
United States
Providence
Burbank, California, 91505
United States
Providence, St. Jude
Fullerton, California, 92835
United States
Providence, Mission
Mission Viejo, California, 92691
United States
Providence, Orange County
Orange, California, 92868
United States
VA Miami Health Care System
Miami, Florida, 33125
United States
James A. Haley Veterans Hospital (VA Tampa)
Tampa, Florida, 33612
United States
Southeast Louisiana Veterans Health Care System (SLVHCS) (VA New Orleans)
New Orleans, Louisiana, 70119
United States
Boston VA Research Institute (VA Boston)
Boston, Massachusetts, 02111-1750
United States
Providence
Portland, Oregon, 97213
United States
VA Pittsburgh Healthcare System
Pittsburgh, Pennsylvania, 15240
United States
VA Wilkes Barre Medical Center
Wilkes-Barre, Pennsylvania, 18711
United States
Carolina Blood and Cancer Care Associate
Lancaster, South Carolina, 29720
United States
Carolina Blood and Cancer Care Associates
Rock Hill, South Carolina, 29732
United States
VA Salt Lake City Health Care System (VASLCHCS)
Salt Lake City, Utah, 84148
United States
WVU University Town Centre Family Medicine
Morgantown, West Virginia, 26501
United States

Collaborators and Investigators

Sponsor: GRAIL, Inc.

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-08-23
Study Completion Date2026-10-30

Study Record Updates

Study Start Date2021-08-23
Study Completion Date2026-10-30

Terms related to this study

Keywords Provided by Researchers

  • Multi-cancer early detection
  • Cancer screening
  • Circulating cell-free tumor DNA

Additional Relevant MeSH Terms

  • Early Detection of Cancer
  • Cancer