Histamine as a Molecular Transducer of Adaptation to Exercise

Description

This study is investigating the role of histamine in generating adaptation to exercise

Conditions

Postexercise Hypotension

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Study Overview

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Study Details

Study overview

This study is investigating the role of histamine in generating adaptation to exercise

Histamine as a Molecular Transducer of Adaptation to Exercise

Histamine as a Molecular Transducer of Adaptation to Exercise

Condition
Postexercise Hypotension
Intervention / Treatment

-

Contacts and Locations

Eugene

University of Oregon, Eugene, Oregon, United States, 97403

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18 -40
  • * Systolic ≥ 120
  • * Diastolic ≥ 80
  • * Body mass index (BMI) ˃ 28 kg/m2
  • * Prior diagnosis of cardiovascular disease, diabetes, autonomic disorders, or asthma
  • * Smoking or nicotine use
  • * Ongoing medical therapy (other than birth control)
  • * Ongoing use of over-the-counter or prescription antihistamines
  • * Allergies or hypersensitivities to drugs, local anesthetics, skin disinfectants, adhesives, or latex
  • * Pregnant, breastfeeding subjects, or planning to become pregnant in the next 12 months
  • * Mobility restrictions that interfere with physical activity
  • * High physical activity based on International Physical Activity Questionaire (IPAQ1)
  • * Non-English speaking

Ages Eligible for Study

18 Years to 40 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Oregon,

John R Halliwill, PhD, PRINCIPAL_INVESTIGATOR, University of Oregon

Study Record Dates

2026-12-31