RECRUITING

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.

Official Title

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Quick Facts

Study Start:2023-03-14
Study Completion:2025-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05219799

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * BMI \>18 kg/m2
  1. * Pregnancy, breastfeeding
  2. * Diagnosed sleep apnea or AHI \>10 events/hr
  3. * Current smoking/Nicotine use
  4. * Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy
  5. * Nerve/neurologic disease
  6. * Cardiovascular, hepatic, renal, respiratory disease
  7. * Blood pressure ≥140/90 mmHg
  8. * Diabetes, Polycystic ovarian syndrome
  9. * Communication barriers
  10. * Prescription medications, Sensitivity to lidocaine

Contacts and Locations

Study Contact

Jacqueline K Limberg, Ph.D.
CONTACT
5738822544
limbergj@missouri.edu

Principal Investigator

Jacqueline Limberg, Ph.D.
PRINCIPAL_INVESTIGATOR
University of Missouri-Columbia

Study Locations (Sites)

University of Missouri
Columbia, Missouri, 65211
United States

Collaborators and Investigators

Sponsor: University of Missouri-Columbia

  • Jacqueline Limberg, Ph.D., PRINCIPAL_INVESTIGATOR, University of Missouri-Columbia

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-14
Study Completion Date2025-07

Study Record Updates

Study Start Date2023-03-14
Study Completion Date2025-07

Terms related to this study

Additional Relevant MeSH Terms

  • Obesity
  • Vasodilation
  • Healthy