Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Description

The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.

Conditions

Obesity, Vasodilation, Healthy

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Study Overview

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Study Details

Study overview

The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Condition
Obesity
Intervention / Treatment

-

Contacts and Locations

Columbia

University of Missouri, Columbia, Missouri, United States, 65211

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * BMI \>18 kg/m2
  • * Pregnancy, breastfeeding
  • * Diagnosed sleep apnea or AHI \>10 events/hr
  • * Current smoking/Nicotine use
  • * Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy
  • * Nerve/neurologic disease
  • * Cardiovascular, hepatic, renal, respiratory disease
  • * Blood pressure ≥140/90 mmHg
  • * Diabetes, Polycystic ovarian syndrome
  • * Communication barriers
  • * Prescription medications, Sensitivity to lidocaine

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Missouri-Columbia,

Jacqueline Limberg, Ph.D., PRINCIPAL_INVESTIGATOR, University of Missouri-Columbia

Study Record Dates

2025-07