RECRUITING

tDCS With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity

Conditions

Obesity transcranial direct current stimulation neuromodulation

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to investigate if transcranial direct current stimulation (tDCS) can increase the effectiveness of cognitive training to reduce impulsivity in individuals with obesity, and to evaluate weight change with these individuals. The long-term goal of this research is to develop new treatment approaches for individuals with obesity.

Official Title

Transcranial Direct Current Stimulation (tDCS) With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity: A Clinical Trial

Quick Facts

Study Start:2022-11-23

Study Completion:2026-04-30

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05225233

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Veteran enrolled in a MOVE! Weight Management Program (group or individual) at the Minneapolis VA Health Care System * Obese (BMI\>30 or BMI\>27 plus at least one weight-related comorbidity) * Adults, ages 18 years or older (up to age 80) * Able to understand English, self-consent and follow study-related procedures * Willing to use a reliable form of birth control if they are of females of child-bearing potential	* History of any of the following: seizures, severe or moderate head injury, head surgery, significant neurological disorder (significance based on Principal Investigator's judgment) * Frequent severe headaches * History of scalp conditions such as eczema or seborrheic dermatitis * Metal in head (other than in mouth) including shrapnel/surgical clips/welding fragments * Implanted medical devices (including pumps and cardiac pacemakers) * Pregnancy * Acute substance dependence or withdrawal that would affect ability to complete cognitive training * Moderately severe to severe depression (as identified on PHQ-9 scale during baseline screening) * Other psychological or medical disorders requiring inpatient treatment (as identified during chart review) * Presence of a known metabolic or hormonal disorder (such as Cushing's, untreated thyroid dysfunction, or uncontrolled diabetes mellitus defined as a hemoglobin A1c \> 8.0), or significant edema/volume overload - all of which would affect weight * Uncontrolled hypothyroidism that would affect weight

Inclusion Criteria

Exclusion Criteria

* Veteran enrolled in a MOVE! Weight Management Program (group or individual) at the Minneapolis VA Health Care System
* Obese (BMI\>30 or BMI\>27 plus at least one weight-related comorbidity)
* Adults, ages 18 years or older (up to age 80)
* Able to understand English, self-consent and follow study-related procedures
* Willing to use a reliable form of birth control if they are of females of child-bearing potential

* History of any of the following: seizures, severe or moderate head injury, head surgery, significant neurological disorder (significance based on Principal Investigator's judgment)
* Frequent severe headaches
* History of scalp conditions such as eczema or seborrheic dermatitis
* Metal in head (other than in mouth) including shrapnel/surgical clips/welding fragments
* Implanted medical devices (including pumps and cardiac pacemakers)
* Pregnancy
* Acute substance dependence or withdrawal that would affect ability to complete cognitive training
* Moderately severe to severe depression (as identified on PHQ-9 scale during baseline screening)
* Other psychological or medical disorders requiring inpatient treatment (as identified during chart review)
* Presence of a known metabolic or hormonal disorder (such as Cushing's, untreated thyroid dysfunction, or uncontrolled diabetes mellitus defined as a hemoglobin A1c \> 8.0), or significant edema/volume overload - all of which would affect weight
* Uncontrolled hypothyroidism that would affect weight

Contacts and Locations

Study Contact

Shalamar D Sibley, MD

CONTACT

(612) 725-2000

Shalamar.Sibley@va.gov

Lisa E Keacher, BS

CONTACT

(612) 467-5203

lisa.keacher@va.gov

Principal Investigator

Shalamar D Sibley, MD

PRINCIPAL_INVESTIGATOR

Minneapolis VA Health Care System, Minneapolis, MN

Study Locations (Sites)

Minneapolis VA Health Care System, Minneapolis, MN

Minneapolis, Minnesota, 55417-2309

United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

Shalamar D Sibley, MD, PRINCIPAL_INVESTIGATOR, Minneapolis VA Health Care System, Minneapolis, MN

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-11-23

Study Completion Date2026-04-30

Study Record Updates

Study Start Date2022-11-23

Study Completion Date2026-04-30

Terms related to this study

Keywords Provided by Researchers

transcranial direct current stimulation
neuromodulation

Additional Relevant MeSH Terms

Obesity