RECRUITING

Secretin in Refeeding

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Patients with restrictive-type anorexia nervosa who are admitted to the hospital for feeding often urinate excessive amounts. Others have changes in the way that they handle acid and base. These issues prolong hospitalizations. Current data suggest that one hormone--named secretin--may control both urine output and how the body handles acid and base. This study will evaluate whether secretin levels are different in anorexic patients who urinate an excessive amount compared to those who urinate normal amounts. For this study, patients will have one extra blood draw before and after one meal during their hospitalization. The blood draw before the meal coincides with a standard of care blood draw. Also after the meal, subjects will be asked to provide one extra urine sample. Information from subject's medical records will also be used.

Official Title

Secretin Levels in Refeeding-induced Polyuria (Cross Section)

Quick Facts

Study Start:2022-02-01
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05235867

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:13 Years to 24 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Group 1:
  2. * male and female patients
  3. * age 13-24 years
  4. * diagnosis of restrictive-type anorexia nervosa
  5. * hospitalization for nutritional support
  6. * \>4 cc/kg/day of urine output (a.k.a. "fluid dumpers"; n=5)
  7. * Group 2:
  8. * male and female patients
  9. * age 13-24 years
  10. * diagnosis of restrictive-type anorexia nervosa
  11. * hospitalization for nutritional support
  12. * \<2 cc/kg/d of urine output (a.k.a. "non-dumpers"; n=5)
  1. * 5150 hold
  2. * Anti-depressant, anti-psychotic, or anticonvulsant medications
  3. * Previous hospitalization within the past 6 months
  4. * Underlying metabolic disorder not related to anorexia nervosa (including chronic kidney disease, renal tubular disorders, and underlying endocrine disorders)
  5. * Pregnancy
  6. * NG or G-tube feeds after day 2 of hospitalization
  7. * \> 10% of nutritional needs from supplemental feeds

Contacts and Locations

Study Contact

Misciel Macaraig
CONTACT
310-825-0922
mbmacaraig@mednet.ucla.edu

Study Locations (Sites)

University of California, Los Angeles (UCLA)
Los Angeles, California, 90095
United States

Collaborators and Investigators

Sponsor: University of California, Los Angeles

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-02-01
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2022-02-01
Study Completion Date2024-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Anorexia in Adolescence