The Effect of a High Fiber Diet and High-Intensity Interval Exercise in Patients With HFpEF

Description

This study is trying to find out how best to improve common measures of health and survival in those diagnosed with heart failure with preserved ejection fraction (HFpEF) through the implementation of 4 weeks of an exercise training program consisting of high intensity interval training, dietary approaches to stop hypertension (DASH diet), or a combination of the two. Currently there are not established guidelines that have been shown to improve clinical end points in those with this HFpEF.

Conditions

Heart Failure With Preserved Ejection Fraction

Study Overview

Study Details

Study overview

This study is trying to find out how best to improve common measures of health and survival in those diagnosed with heart failure with preserved ejection fraction (HFpEF) through the implementation of 4 weeks of an exercise training program consisting of high intensity interval training, dietary approaches to stop hypertension (DASH diet), or a combination of the two. Currently there are not established guidelines that have been shown to improve clinical end points in those with this HFpEF.

The Effect of a High Fiber Diet and High-Intensity Interval Exercise in Patients With Heart Failure With Preserved Ejection Fraction

The Effect of a High Fiber Diet and High-Intensity Interval Exercise in Patients With HFpEF

Condition
Heart Failure With Preserved Ejection Fraction
Intervention / Treatment

-

Contacts and Locations

Charlottesville

University of Virginia University Hospital, Charlottesville, Virginia, United States, 22903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * ≥40 years of age
  • * Diagnosed with heart failure with preserved ejection fraction
  • * NYHA class II-III symptoms
  • * Physician clearance to undergo exercise training
  • * Physician clearance to consume DASH diet
  • * Complete COVID-19 vaccination status
  • * Unstable angina
  • * Myocardial infarction in the past 4 weeks
  • * Uncompensated heart failure
  • * NYHA class IV symptoms
  • * Complex ventricular arrhythmias
  • * Musculoskeletal contraindications to stationary bicycling exercise
  • * Symptomatic severe aortic stenosis
  • * Acute pulmonary embolus
  • * Acute myocarditis
  • * Uncontrolled hypertension
  • * Medication non-compliance
  • * Unable to follow DASH diet
  • * Food allergies (Nuts, wheat)
  • * Pregnant women

Ages Eligible for Study

40 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Virginia,

Siddhartha S Angadi, PhD, PRINCIPAL_INVESTIGATOR, University of Virginia

Study Record Dates

2025-08-01