Computer Monitor vs Augmented Reality 3MDR for PTSD PTSD: A Randomized Controlled Trial

Description

This is a prospective randomized controlled trial comparing two ways of delivering Motion-assisted, Multi-modular Memory Desensitization and Reconsolidation (3MDR) therapy for posttraumatic stress disorder (PTSD). The study seeks 60 volunteers who have PTSD and are eligible for care in the Department of Defense healthcare system. There will be 10-14 therapy sessions that are 60-90 minutes long, about once a week, and symptoms will be assessed before and after the therapy as well as 3 and 6 months after completing therapy. 3MDR asks you to choose pictures and music that are integrated into a virtual reality environment. You will be walking on a treadmill throughout each therapy session, while the therapist stands next to the treadmill and asks you questions about the pictures you chose.

Conditions

Stress Disorders, Post-Traumatic

Study Overview

Study Details

Study overview

This is a prospective randomized controlled trial comparing two ways of delivering Motion-assisted, Multi-modular Memory Desensitization and Reconsolidation (3MDR) therapy for posttraumatic stress disorder (PTSD). The study seeks 60 volunteers who have PTSD and are eligible for care in the Department of Defense healthcare system. There will be 10-14 therapy sessions that are 60-90 minutes long, about once a week, and symptoms will be assessed before and after the therapy as well as 3 and 6 months after completing therapy. 3MDR asks you to choose pictures and music that are integrated into a virtual reality environment. You will be walking on a treadmill throughout each therapy session, while the therapist stands next to the treadmill and asks you questions about the pictures you chose.

Computer Monitor Versus Augmented Reality: Expanding 3MDR Therapy for PTSD

Computer Monitor vs Augmented Reality 3MDR for PTSD PTSD: A Randomized Controlled Trial

Condition
Stress Disorders, Post-Traumatic
Intervention / Treatment

-

Contacts and Locations

Bethesda

Uniformed Services University, Bethesda, Maryland, United States, 20814

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Service member, veteran, retiree, or DEERS-eligible dependent, male or female, at least 18 years or older
  • * Diagnosis of PTSD, as confirmed by the CAPS-5
  • * Able to ambulate with contact guard assistance or less, and walk unassisted on a treadmill, at a normal pace, for up to 90 minutes continuously
  • * History of epilepsy or a seizure disorder, other than febrile seizures that occurred during childhood and have not recurred since
  • * History of a psychotic disorder, bipolar disorder, or active suicidal or homicidal ideation
  • * Use of benzodiazepines on a regular basis within the previous 30 days

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Uniformed Services University of the Health Sciences,

Michael Roy, MD, MPH, PRINCIPAL_INVESTIGATOR, Unformed Services University

Study Record Dates

2026-04-30