RECRUITING

Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature B-cell non-Hodgkin lymphoma (MB-NHL) and classical Hodgkin lymphoma (cHL).

Official Title

Reducing the Burden of Oncologic Chemoradiotherapy And Radiation Exposure From Diagnostic Imaging by Utilizing Targeted Immunotherapy in Children, Adolescents and Young Adults With Lymphoma

Quick Facts

Study Start:2022-02-01
Study Completion:2028-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05253495

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:3 Years to 39 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Newly diagnosed patients with histologically or cytologically proven newly diagnosed MB-NHL or cHL according to WHO Classification who meet the following criteria are eligible:
  2. * Adequate organ function
  1. * Primary mediastinal B-cell lymphoma (PMBL)
  2. * T-cell/histiocyte-rich large B-cell lymphoma
  3. * Gray zone lymphoma
  4. * Follicular lymphoma
  5. * Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL)
  6. * Posttransplant lymphoproliferative lymphoma (PTLD)

Contacts and Locations

Study Contact

Mitchell Cairo, MD
CONTACT
9145942150
mitchell_cairo@nymc.edu
Lauren Harrison, RN
CONTACT
617-285-7844
lauren_harrison@nymc.edu

Principal Investigator

Mitchell Cairo, MD
PRINCIPAL_INVESTIGATOR
New York Medical Center

Study Locations (Sites)

University of Alabama
Birmingham, Alabama, 35233
United States
University of Flordia
Gainesville, Florida, 32610
United States
New York Medical College
Valhalla, New York, 10595
United States

Collaborators and Investigators

Sponsor: New York Medical College

  • Mitchell Cairo, MD, PRINCIPAL_INVESTIGATOR, New York Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-02-01
Study Completion Date2028-06-30

Study Record Updates

Study Start Date2022-02-01
Study Completion Date2028-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Non-hodgkin Lymphoma
  • Hodgkin Lymphoma