Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy

Description

This study is designed as a randomized controlled trial with patients assigned to neuromuscular reversal with either sugammadex or neostigmine/glycopyrrolate reversal. The study will not be blinded to the anesthesiologist to allow for appropriate decision-making on timing and dosage of reversal. This is a single-center study.

Conditions

Appendicitis, Surgery

Study Overview

Study Details

Study overview

This study is designed as a randomized controlled trial with patients assigned to neuromuscular reversal with either sugammadex or neostigmine/glycopyrrolate reversal. The study will not be blinded to the anesthesiologist to allow for appropriate decision-making on timing and dosage of reversal. This is a single-center study.

Effectiveness of Sugammadex Versus Neostigmine on Neuromuscular Reversal in Pediatric Patients Undergoing Laparoscopic Appendectomy for Acute Appendicitis: A Randomized Controlled Trial

Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy

Condition
Appendicitis
Intervention / Treatment

-

Contacts and Locations

Atlanta

Children's Healthcare of Altanta, Atlanta, Georgia, United States, 30322

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients 2-17 years of age
  • * Diagnosis of acute appendicitis
  • * Patient undergoing laparoscopic appendectomy at Children's Healthcare of Atlanta- Egleston.
  • * Parent or Legal Authorized Representative willing to participate, able to understand and sign an informed consent
  • * Patient with an allergy to Sugammadex or Neostigmine
  • * History of renal dysfunction
  • * Parent or legal guardian unwilling or unable or unable to understand the informed consent

Ages Eligible for Study

2 Years to 17 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Emory University,

Laura Gilbertson, MD, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

2025-11-01