Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms

Description

The aim of this study is to determine the principal time cue (light or meals) for resetting circadian rhythms in melatonin and metabolic outcomes.

Conditions

Light Exposure, Meal Timing

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Study Overview

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Study Details

Study overview

The aim of this study is to determine the principal time cue (light or meals) for resetting circadian rhythms in melatonin and metabolic outcomes.

Determining the Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms in Humans

Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms

Condition
Light Exposure
Intervention / Treatment

-

Contacts and Locations

Boston

Brigham and Women's Hospital, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Aged between 18-30 years
  • * Healthy (no medical, psychiatric or sleep disorders;
  • * Non-smoking for at least 6 months;
  • * Body Mass Index of \>18 or \<30 kg/m2;
  • * Able to maintain 8-hour consistent sleep schedule during the study
  • * Able to refrain from caffeine, alcohol, medication and supplements during the study
  • * History of alcohol or substance abuse;
  • * Positive result on drugs of abuse urine toxicology;
  • * Current or past history of sleep disorders, including but not limited to obstructive sleep apnea, narcolepsy, insomnia, or any significant sleep complaint
  • * Psychiatric disorder, or first degree relative with a psychiatric disorder
  • * Recent acute or chronic medical disorder
  • * Use of drugs or medication (birth control OK) likely to affect sleep, alertness or light sensitivity, as determined by the investigators
  • * Visual disorder, including but not limited to color blindness, or family history of glaucoma
  • * Pregnancy or lactation
  • * Shift work (past 3 years)
  • * Transmeridian travel (2 or more time zones) in the past 3 months
  • * Any other reason as determine by the Principal Investigator

Ages Eligible for Study

18 Years to 30 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Brigham and Women's Hospital,

Study Record Dates

2025-09-30