RECRUITING

Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.

Official Title

Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

Quick Facts

Study Start:2022-03-22
Study Completion:2026-02-28
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05277025

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ages 18-70
  2. * Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM
  3. * Fulfills the 2010 ACR-EULAR classification criteria for RA
  4. * Healthy volunteers: No significant pain/fatigue/depression/anxiety.
  1. * Diabetes
  2. * Cancer
  3. * Advanced liver, kidney or cardiovascular disease
  4. * Neuropathic pain

Contacts and Locations

Study Contact

Roland Staud, M.D.
CONTACT
352-294-8200
staudr@ufl.edu
Melyssa M Godfrey, BS
CONTACT
352-265-8901
melyssa.m.g@ufl.edu

Principal Investigator

Roland Staud, M.D.
PRINCIPAL_INVESTIGATOR
University of Florida

Study Locations (Sites)

University of Florida
Gainesville, Florida, 32610
United States

Collaborators and Investigators

Sponsor: University of Florida

  • Roland Staud, M.D., PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-03-22
Study Completion Date2026-02-28

Study Record Updates

Study Start Date2022-03-22
Study Completion Date2026-02-28

Terms related to this study

Additional Relevant MeSH Terms

  • Fibromyalgia
  • Rheumatoid Arthritis