Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * All subjects:
- * Race/ethnicity: any
- * Subject has no history of active Tuberculosis in the last 2 years.
- * NTM culture positive from respiratory specimen (sputum or bronchial lavage fluid)
- * Subject must have an available sputum sample that was taken in the last 2 years. If a sample is not available, the subject must be willing and able to provide a sputum sample.
- * Meets the following Infectious Diseases Society of America (IDSA) criteria for NTM lung disease:
- * 2 or more sputum (or 1 bronchoscopy/biopsy) cultures positive for "Mycobacterium Avium Complex" or "Mycobacterium abscessus) within the last 2 years.
- * Nodules, cavities, and/or bronchiectasis on CT scan within the past 2 years
- * If if the above data are not available, but a patient's Infectious Disease or Pulmonary physician has documented the diagnosis of NTM lung disease in their notes, this will suffice
- * Newly diagnosed with NTM lung disease and beginning antibiotics for NTM within the last 3 months from enrollment.
- * Prior diagnosis of NTM lung disease, and starting initial therapy within the last 3 months prior to enrollment.
- * Consent to pharmacokinetic testing within one month of enrollment and at six months of therapy
- * List the criteria for exclusion
- * Age \< 18 years
- * Subject has cystic fibrosis or other inherited disorders of airway ciliary dysfunction (eg, primary ciliary dyskinesia)
- * Unable to participate in follow-up requirements by phone or clinic visit
Ages Eligible for Study
18 Years to
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
No