COMPLETED

Dual Use of ENDS and Combustible Cigarettes

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study investigates the degree to which shared behavioral processes underlie combustible cigarette (CC) and electronic nicotine delivery system (ENDS) use in young adult dual users of these products in both the laboratory and natural environment. The primary processes examined by this study are cue-reactivity, attentional bias, and affect. Laboratory hypotheses are: (1) cue exposure will elicit craving of both CC and ENDS in the laboratory and that product-specific cues will elicit stronger craving for the affiliated products; (2) visual probe effects indicating attentional bias in the laboratory will be observed for smoking and vaping images; and (3) cross-conditioning from the first hypothesis will be associated with heaviness of use of CC and ENDS and product choice. Natural environment hypotheses are: (1) presence of tobacco-related cues in the natural environment will elicit craving and use of these products; (2) reactivity to cues, attentional bias, and cross-product conditioning assessed in the laboratory will be associated with craving and use of tobacco products over and above the effects of cues in the natural environment; and (3) negative affect will strengthen these associations.

Official Title

Dual Use of ENDS and Combustible Cigarettes: Shared, Distinct, and Cross-Conditioned Processes

Quick Facts

Study Start:2022-12-14
Study Completion:2025-05-20
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT05280535

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years to 34 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 21 to 34 (inclusive)
  2. * English-speaking at an 8th grade level
  3. * Any self-reported past 7-day use of both ENDS and cigarettes
  4. * Self-identification as a regular ENDS and combustible cigarette user OR use of cigarettes and e-cigarettes on at least 6 of the past 7 days including at least 3 days of using each product;
  5. * Smoking status confirmed via breath CO \>= 6 ppm112 or NicAlert test of urine cotinine (level \>= 3)
  6. * Smartphone ownership.
  1. * Intention to quit smoking or vaping during the next 30 days
  2. * Intention to travel during next 30 days
  3. * Current alcohol dependence (based on MINI)
  4. * Urine-screened or past month illicit substance use other than marijuana (amphetamine, cocaine, methamphetamine, opioids, benzodiazepines
  5. * Pregnant (due to toxicity of tobacco products)
  6. * Current psychosis, mania, or suicidal ideation (based on MINI).

Contacts and Locations

Study Locations (Sites)

Center for Alcohol and Addiction Studies
Providence, Rhode Island, 02903
United States

Collaborators and Investigators

Sponsor: Brown University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-12-14
Study Completion Date2025-05-20

Study Record Updates

Study Start Date2022-12-14
Study Completion Date2025-05-20

Terms related to this study

Keywords Provided by Researchers

  • cigarette
  • e-cigarette
  • ENDS
  • electronic nicotine delivery system
  • smoking
  • vaping
  • attentional bias
  • cue reactivity
  • negative affect
  • craving

Additional Relevant MeSH Terms

  • Smoking, Cigarette
  • Electronic Cigarette Use