Carbon Dioxide (CO2) and Cognitive Impairment

Description

The purpose of the study is to better understand the biological mechanisms of carbon dioxide (CO2)-induced cognitive impairments.

Conditions

Healthy

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Study Overview

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Study Details

Study overview

The purpose of the study is to better understand the biological mechanisms of carbon dioxide (CO2)-induced cognitive impairments.

Carbon Dioxide (CO2): A Pilot Study of a Hypothesized Mechanism to Explain Cognitive Impairment

Carbon Dioxide (CO2) and Cognitive Impairment

Condition
Healthy
Intervention / Treatment

-

Contacts and Locations

Piscataway

Rutgers - EOHSI, Piscataway, New Jersey, United States, 08854

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * History of COVID-19 vaccination
  • * Weigh at least 110 pounds
  • * Colorblindness
  • * Inability to hear verbal instructions
  • * Cardiovascular disease, including a history of stroke
  • * Diabetes requiring the use of insulin
  • * Pregnancy
  • * Current asthma (an asthma attack within the past five years)
  • * Medications for or history of anxiety disorder diagnosis or panic attacks
  • * Medications which may affect cognition such as beta-blockers and CNS depressants
  • * Respiratory symptoms in the previous four weeks
  • * Use of sedating cold/allergy medications in the previous week
  • * Use of marijuana in the previous week
  • * Consumption of alcohol in the previous 24 hours
  • * History of head trauma or neurosurgery or neurological disorder
  • * Ferrous metal implanted in or on the body, electrical devices such as a pacemaker, nonremovable ferrous jewelry
  • * Surgical pins or plates above the neck
  • * History of eye injury involving metallic materials, shavings in eyes, or welding without a face mask
  • * Lead or iron tatoos
  • * Claustrophobia
  • * Back problems that would prevent the subject from laying still comfortably for up to 90 minutes
  • * Current or recent contact lens use

Ages Eligible for Study

18 Years to 30 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Rutgers, The State University of New Jersey,

Howard Kipen, MD, PRINCIPAL_INVESTIGATOR, Professor

Study Record Dates

2025-06-01