CHOICES3: Sickle Cell Disease Parenting CHOICES

Description

The study will use web-based data collection (SCKnowIQ) and intervention delivery strategies enhanced by nudges and tailored boosters in a sample of 430 adult men and women, aged 18-45 yr with SCD (Sickle Cell Disease) or SCT (Sickle Cell Trait), at-risk, and planning within 2 years to have a child free of SCD.

Conditions

Sickle Cell Disease, Sickle Cell Trait

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Study Overview

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Study Details

Study overview

The study will use web-based data collection (SCKnowIQ) and intervention delivery strategies enhanced by nudges and tailored boosters in a sample of 430 adult men and women, aged 18-45 yr with SCD (Sickle Cell Disease) or SCT (Sickle Cell Trait), at-risk, and planning within 2 years to have a child free of SCD.

CHOICES for Sickle Cell Reproductive Health: Randomized Clinical Trial (RCT) of a Preconception Intervention Model for a Single Gene Disorder

CHOICES3: Sickle Cell Disease Parenting CHOICES

Condition
Sickle Cell Disease
Intervention / Treatment

-

Contacts and Locations

Gainesville

University of Florida, Gainesville, Florida, United States, 32611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of SCD (HbSS, HbSC (Hemoglobin Sickle C Disease), HbS-beta-0 thalassemia, and HbS-beta+ thalassemia) or report of SCT (SCD is Hgb electrophoresis confirmed; SCT evaluated by SickleScan);
  • * Able and intends to conceive a child in the next 2 years (first child or another child);
  • * Speaks and reads English;
  • * 18 to 45 years;
  • * At-risk for having a child with SCD (i.e., sexual/ reproductive partner has SCD, SCT, or unknown sickle cell status); and
  • * Wants to avoid the risk of a child with SCD.
  • * The age range is based on typical reproductive age for SCD where median survival is 42 years for men and 48 years for women.
  • * Legally blind;
  • * Physically unable to complete the study questionnaires or the intervention;
  • * Report health history of hysterectomy, tubal ligation, medically or surgically induced menopause, or vasectomy that would
  • * Prevent ability to bear children;
  • * Report a desire to remain childless or have no further children;
  • * Report knowing or being a relative or friend of a participant previously enrolled in the study, or
  • * Previous participation in a CHOICES study.

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Florida,

Diana Wilkie, PhD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

2025-06-30