RECRUITING

OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Hypertension (HTN) has a greater impact on African Americans (AA) than any other U.S. racial group. Uncontrolled blood pressure (BP) contributes to higher rates of disability, death, and health resource use among AA. HTN is the single most influential risk factor for cardiovascular disease (CVD), as well as a risk factor for the incidence of stroke, diabetes, chronic kidney disease, and dementia. Importantly, older adults account for 15% of the U.S. population, and two-thirds of older adults over age 60 have HTN, with higher rates observed in AA older adults. Strategies to support self-managing HTN and BP control are crucial as the older population is projected to age considerably and become more racially and ethnically diverse. Research has documented the negative effects on health and health outcomes of poorly controlled BP and is one of the most important modifiable CVD risk factors. Lower BP targets will require aggressive management and an increase in antihypertensive medications. Therefore, to achieve lower targets in this population, greater efforts, including patient-centered methods will be needed to support self-managing HTN, especially in terms of medication adherence. As we shifted into the digital age, the use of mHealth technologies (smart phones, applications, SMS or text messaging) has been a powerful approach and mechanism for the treatment and management of chronic diseases. However, behavioral interventions that incorporate technology do not reach minorities or disadvantaged AA older adults with HTN. OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP) will leverage existing knowledge of effective technology-based components for HTN self-management to support and improve BP control using unique aspects of mHealth platforms in AA older adults. Findings from this study, if confirmed, will improve BP control and support self-managing HTN, as well as has the potential to close the health disparity gap between AA and non-AA older adults with HTN.

Official Title

OPtimizing Technology to Improve Medication Adherence and Blood Pressure Control

Quick Facts

Study Start:2021-02-14
Study Completion:2026-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05293756

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Self-identify as African American
  2. 2. 50 years of age or older
  3. 3. Diagnosed with hypertension, with a systolic blood pressure≥ 130 mmHg but less than 170 mmHg
  4. 4. Prescribed at least two hypertensive, one of which is a diuretic/thiazide and or calcium channel blocker antihypertensive medication
  5. 5. Own a smartphone with a data plan, the capability to download the Medisafe app, or view videos
  6. 6. Able to read/understand English
  1. 1. Unable to give informed consent or judged to have impaired cognitive ability or severe memory
  2. 2. Currently using a medication management application (app)
  3. 3. Experienced a major CVD event or procedure (e.g., myocardial infarction, stroke, heart surgery) within the past year
  4. 4. Patients with a diagnosis of chronic kidney disease (defined as estimated glomerular filtration rate (eGFR) \< 60 ml/min/1.73m2) and/or receiving dialysis.

Contacts and Locations

Study Contact

Carolyn Still, PhD
CONTACT
216-368-6338
carolyn.still@case.edu

Principal Investigator

Carolyn Still, PhD
PRINCIPAL_INVESTIGATOR
Case Western Reserve University, School of Nursing

Study Locations (Sites)

Case Western Reserve University
Cleveland, Ohio, 44143
United States

Collaborators and Investigators

Sponsor: Case Western Reserve University

  • Carolyn Still, PhD, PRINCIPAL_INVESTIGATOR, Case Western Reserve University, School of Nursing

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-02-14
Study Completion Date2026-05-31

Study Record Updates

Study Start Date2021-02-14
Study Completion Date2026-05-31

Terms related to this study

Keywords Provided by Researchers

  • Hypertension
  • Self-Management
  • Home Blood Pressure Monitoring

Additional Relevant MeSH Terms

  • Hypertension
  • Self-Management
  • Technology
  • Quality of Life