Remote Dynamic Cycling for the Customized Off-site Rehab in Parkinson's Disease

Description

This research will develop novel and accessible way to deliver effective and customized rehab to those suffering from common and devastating neurodegenerative condition called Parkinson's disease. The investigators will examine the efficacy of novel rehab technique that can be monitored and modified in real-time but over virtual interface using a remotely located device in a paradigm called dynamic cycling. This technology will benefit thousands of Veterans who need customized and cost-effective rehab but cannot travel to specialized facilities due to inevitable limitations such as pandemics or because of lack of resources, social support, frailty, or home-bound status.

Conditions

Parkinson's Disease

Study Overview

Study Details

Study overview

This research will develop novel and accessible way to deliver effective and customized rehab to those suffering from common and devastating neurodegenerative condition called Parkinson's disease. The investigators will examine the efficacy of novel rehab technique that can be monitored and modified in real-time but over virtual interface using a remotely located device in a paradigm called dynamic cycling. This technology will benefit thousands of Veterans who need customized and cost-effective rehab but cannot travel to specialized facilities due to inevitable limitations such as pandemics or because of lack of resources, social support, frailty, or home-bound status.

Remote Dynamic Cycling for the Customized Off-site Rehab in Parkinson's Disease

Remote Dynamic Cycling for the Customized Off-site Rehab in Parkinson's Disease

Condition
Parkinson's Disease
Intervention / Treatment

-

Contacts and Locations

Cleveland

Louis Stokes VA Medical Center, Cleveland, OH, Cleveland, Ohio, United States, 44106-1702

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Ability to perform informed consent.
  • * Hoehn and Yahr (H\&Y) stages I-III when off medication,
  • * Stable medical regimen of antiparkinsonian medication for at least six months
  • * Montreal Cognitive Assessment Scoreless than 18
  • * Hamilton depression score of 20 or higher
  • * Hamilton anxiety rating score greater than 24
  • * Clinical diagnosis including perinatal brain injury, stroke, and atypical parkinsonism
  • * One or more signs or symptoms of untreated cardiovascular disease including Pain, discomfort in the chest, neck, jaw, arms or other areas that may result from ischemia - Shortness of breath at rest or with mild exertion - Dizziness or syncope - Orthopnea or paroxysmal nocturnal dyspnea - Ankle edema - Palpitations or tachycardia - Intermittent claudication - heart murmur - Unusual fatigue or shortness of breath with usual activity (ACSM Cardiovascular Risk Assessment)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

VA Office of Research and Development,

Aasef G. Shaikh, MD PhD, PRINCIPAL_INVESTIGATOR, Louis Stokes VA Medical Center, Cleveland, OH

Study Record Dates

2026-03-31