RECRUITING

Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication resistant AH.

Official Title

Real-time fMRI Neurofeedback as a Tool to Mitigate Auditory Hallucinations in Patients With Schizophrenia - R33 Phase

Quick Facts

Study Start:2022-03-01
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05299749

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 55 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * patients diagnosed with SZ or schizoaffective disorder using DSM-5 criteria
  2. * auditory hallucinations not responsive to pharmacology as determined by chart review and a clinical interview of SCID.
  1. * neurologic illness
  2. * major head trauma
  3. * electroconvulsive therapy
  4. * alcohol or drug dependence
  5. * alcohol or drug abuse within the past five years
  6. * verbal IQ below 70

Contacts and Locations

Study Contact

margaret niznikiewicz, PhD
CONTACT
6176534627
margaret_niznikiewicz@hms.harvard.edu
Clemens Bauer, phd
CONTACT
617-870-1771
c.bauer@northeastern.edu

Principal Investigator

margaret niznikiewicz
PRINCIPAL_INVESTIGATOR
Boston VA Research Institute, Inc.

Study Locations (Sites)

Boston VA Healthcare System, Brockton
Brockton, Massachusetts, 02301
United States

Collaborators and Investigators

Sponsor: Boston VA Research Institute, Inc.

  • margaret niznikiewicz, PRINCIPAL_INVESTIGATOR, Boston VA Research Institute, Inc.

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-03-01
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2022-03-01
Study Completion Date2025-06-30

Terms related to this study

Keywords Provided by Researchers

  • Auditory-Hallucination
  • Connectivity
  • brain-activity
  • default-mode-network
  • superior temporal gyrus
  • Neurofeedback
  • MRI

Additional Relevant MeSH Terms

  • Schizophrenia
  • Auditory Hallucination
  • Treatment-resistant Schizophrenia