Feasibility of Early Gabapentin as an Intervention for Neurorecovery

Description

The objective of the proposed study is to conduct the first ever prospective, dose-exploration trial to test the feasibility of early administration of gabapentin as an intervention for neurorecovery. This research project falls under the Intervention Development stage of research as the primary goal is to assess the feasibility of conducting a well-designed intervention efficacy study in the future.

Conditions

Spinal Cord Injuries

Study Overview

Study Details

Study overview

The objective of the proposed study is to conduct the first ever prospective, dose-exploration trial to test the feasibility of early administration of gabapentin as an intervention for neurorecovery. This research project falls under the Intervention Development stage of research as the primary goal is to assess the feasibility of conducting a well-designed intervention efficacy study in the future.

Feasibility of Early Gabapentin as an Intervention for Neurorecovery

Feasibility of Early Gabapentin as an Intervention for Neurorecovery

Condition
Spinal Cord Injuries
Intervention / Treatment

-

Contacts and Locations

Cleveland

MetroHealth Medical Center, Cleveland, Ohio, United States, 44109

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Traumatic SCI;
  • 2. All levels of SCI;
  • 3. All severities of SCI, AIS A-D;
  • 4. Age 18 years and older.
  • 5. Agree to participate and start study drug within 120 hours' post-injury.
  • 6. Adequate cognition and communication to provide informed consent
  • 1. Presence of moderate/severe traumatic brain injury (TBI) as defined by Glasgow Coma Score (GCS) \< 13 at 120 hours' post-injury.
  • 2. Documented use of gabapentinoids at the time of injury.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

MetroHealth Medical Center,

Dr. Kimberly Anderson, PhD, PRINCIPAL_INVESTIGATOR, Metrohealth Medical Center-Case Western Reserve University School of Medicine

Study Record Dates

2026-08-31