RECRUITING

Liver Cancer Disparities in American Indian and Alaska Native Persons

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

We are performing a pilot and feasibility randomized controlled trial (RCT) of HCC screening by US + AFP every 6 months (n=100), the current standard-of-care, versus aMRI + AFP every 6 months (n=100) for 12 months (i.e. at time 0, 6 and 12 months) among AI/AN patients with cirrhosis or HBV.

Official Title

Liver Cancer Disparities in American Indian and Alaska Native Persons

Quick Facts

Study Start:2022-04-01
Study Completion:2026-09-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05304234

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Cirrhosis, any etiology, or chronic HBV infection
  2. * High risk of HCC
  3. * Age 18-75
  4. * Competent to provide informed consent
  1. * Prior diagnosis of HCC
  2. * Current suspicion of HCC
  3. * Prior receipt of any organ transplantation
  4. * Participation in another HCC screening trial
  5. * CTP score \>=10
  6. * MELD-Na score \>20
  7. * GFR\<30
  8. * Poor life expectancy (\<5 years)
  9. * Contraindication to MRI
  10. * Inability to complete study visits
  11. * Currently pregnant

Contacts and Locations

Study Contact

Jennifer R Harry
CONTACT
206-616-0397
jharry@medicine.washington.edu
Stephanie Y Park
CONTACT
206-744-7050
sypark22@uw.edu

Principal Investigator

George Ioannou, MD, MS
PRINCIPAL_INVESTIGATOR
University of Washington

Study Locations (Sites)

Cherokee Nation Health Service
Tahlequah, Oklahoma, 74464
United States

Collaborators and Investigators

Sponsor: University of Washington

  • George Ioannou, MD, MS, PRINCIPAL_INVESTIGATOR, University of Washington

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-01
Study Completion Date2026-09-01

Study Record Updates

Study Start Date2022-04-01
Study Completion Date2026-09-01

Terms related to this study

Additional Relevant MeSH Terms

  • Hepatocellular Carcinoma
  • Cirrhosis, Liver
  • Hepatitis B