RECRUITING

Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to assess the safety and immunogenicity of amezosvatein (CRV-101), an investigational vaccine compared to Shingrix® for the prevention of herpes zoster in adults aged 50 years and older

Official Title

A Randomized, Observer-Blind, Phase 2 Study To Assess the Safety and Immunogenicity of CRV-101 Vaccine Head-To-Head With SHINGRIX® for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older

Quick Facts

Study Start:2022-02-02
Study Completion:2032-03-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05304351

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Clinical Operations
CONTACT
206-492-5722
clinopscrv101@curevovaccine.com
Curevo Inc
CONTACT
206-492-5722
TM@curevovaccine.com

Principal Investigator

Lisa Shelton, ARNP
STUDY_DIRECTOR
Curevo Inc
Guy De La Rosa, MD
STUDY_DIRECTOR
Curevo Inc

Study Locations (Sites)

Curevo Investigational Site
Tempe, Arizona, 85281
United States
Curevo Investigational Site
Coral Gables, Florida, 33134
United States
Curevo Investigational Site
Oak Brook, Illinois, 60523
United States
Curevo Investigational Site
Lenexa, Kansas, 66219
United States
Curevo Investigational Site
Newton, Kansas, 67114
United States
Curevo Investigational Site
Lexington, Kentucky, 40509
United States
Curevo Investigational Site
Las Vegas, Nevada, 89119
United States
Curevo Investigational Site
Edmond, Oklahoma, 73013
United States
Curevo Investigational Site
Knoxville, Tennessee, 37909
United States
Curevo Investigational Site
Austin, Texas, 78745
United States
Curevo Investigational Site
Dallas, Texas, 75251
United States
Curevo Investigational Site
Euless, Texas, 76040
United States
Curevo Investigational Site
Salt Lake City, Utah, 84107
United States

Collaborators and Investigators

Sponsor: Curevo Inc

  • Lisa Shelton, ARNP, STUDY_DIRECTOR, Curevo Inc
  • Guy De La Rosa, MD, STUDY_DIRECTOR, Curevo Inc

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-02-02
Study Completion Date2032-03-06

Study Record Updates

Study Start Date2022-02-02
Study Completion Date2032-03-06

Terms related to this study

Keywords Provided by Researchers

  • Herpes Zoster
  • Shingles
  • Varicella Zoster Virus
  • Vaccine

Additional Relevant MeSH Terms

  • Herpes Zoster
  • Shingles