RECRUITING

PREventing Pain After Surgery

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use. Investigators will then assess the acceptability, feasibility, and preliminary efficacy of the finalized intervention to prevent the transition to CPSP and reduce post-surgical opioid use six months following lumbar spine surgery. Finally, investigators will identify psychosocial and psychophysical phenotypes associated with response to this intervention.

Official Title

PREventing Pain After Surgery: a Feasibility and Acceptability Study of Acceptance and Commitment Therapy for the Prevention of Chronic Post-surgical Pain (PREPS)

Quick Facts

Study Start:2023-01-13
Study Completion:2026-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05306665

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:22 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * scheduled to undergo fusion, discectomy, vertebroplasty, kyphoplasty, or foraminotomy
  2. * age 22 and older
  3. * able to communicate fluently in English
  1. * inability to complete study procedures due to delirium, dementia, psychosis, or other cognitive impairment
  2. * have a history of severe neurologic movement disorder
  3. * are pregnant or intent to become pregnant during study
  4. * have undergone previous spinal surgery
  5. * have spinal deformity, pseudarthrosis, trauma, infection, or tumor as primary indication for surgery
  6. * have undergone Acceptance and Commitment Therapy in last 2 years

Contacts and Locations

Study Contact

Samantha M Meints, PhD
CONTACT
6177329014
smeints@bwh.harvard.edu
Marise Cornelius, MBA
CONTACT
mcornelius@bwh.harvard.edu

Study Locations (Sites)

Brigham and Women's Hospital
Chestnut Hill, Massachusetts, 01467
United States

Collaborators and Investigators

Sponsor: Brigham and Women's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-13
Study Completion Date2026-08-01

Study Record Updates

Study Start Date2023-01-13
Study Completion Date2026-08-01

Terms related to this study

Keywords Provided by Researchers

  • Chronic pain
  • Surgery
  • opioid
  • acceptance and commitment therapy
  • Prevention

Additional Relevant MeSH Terms

  • Pain, Back
  • Spinal Stenosis
  • Disc Herniation
  • Spondylosis
  • Spondylolisthesis
  • Back Injuries