PREventing Pain After Surgery

Description

The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use. Investigators will then assess the acceptability, feasibility, and preliminary efficacy of the finalized intervention to prevent the transition to CPSP and reduce post-surgical opioid use six months following lumbar spine surgery. Finally, investigators will identify psychosocial and psychophysical phenotypes associated with response to this intervention.

Conditions

Pain, Back, Spinal Stenosis, Disc Herniation, Spondylosis, Spondylolisthesis, Back Injuries

Study Overview

Study Details

Study overview

The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use. Investigators will then assess the acceptability, feasibility, and preliminary efficacy of the finalized intervention to prevent the transition to CPSP and reduce post-surgical opioid use six months following lumbar spine surgery. Finally, investigators will identify psychosocial and psychophysical phenotypes associated with response to this intervention.

PREventing Pain After Surgery: a Feasibility and Acceptability Study of Acceptance and Commitment Therapy for the Prevention of Chronic Post-surgical Pain (PREPS)

PREventing Pain After Surgery

Condition
Pain, Back
Intervention / Treatment

-

Contacts and Locations

Chestnut Hill

Brigham and Women's Hospital, Chestnut Hill, Massachusetts, United States, 01467

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * scheduled to undergo fusion, discectomy, vertebroplasty, kyphoplasty, or foraminotomy
  • * age 22 and older
  • * able to communicate fluently in English
  • * inability to complete study procedures due to delirium, dementia, psychosis, or other cognitive impairment
  • * have a history of severe neurologic movement disorder
  • * are pregnant or intent to become pregnant during study
  • * have undergone previous spinal surgery
  • * have spinal deformity, pseudarthrosis, trauma, infection, or tumor as primary indication for surgery
  • * have undergone Acceptance and Commitment Therapy in last 2 years

Ages Eligible for Study

22 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Brigham and Women's Hospital,

Study Record Dates

2026-08-01