Venetoclax to Augment Epigenetic Modification and Chemotherapy

Description

The investigator is testing the addition of venetoclax to 5-azacitidine and vorinostat followed by standard chemotherapy to enhance treatment response in AML patients.

Conditions

Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory

Study Overview

Study Details

Study overview

The investigator is testing the addition of venetoclax to 5-azacitidine and vorinostat followed by standard chemotherapy to enhance treatment response in AML patients.

A Phase I Study of Venetoclax to Augment Epigenetic Modification and Chemotherapy in Pediatric and Young Adult Patients With Relapsed and Refractory Acute Myeloid Leukemia

Venetoclax to Augment Epigenetic Modification and Chemotherapy

Condition
Acute Myeloid Leukemia, in Relapse
Intervention / Treatment

-

Contacts and Locations

Milwaukee

Children's Wisconsin, Milwaukee, Wisconsin, United States, 53226

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    1 Year to 25 Years

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Medical College of Wisconsin,

    Michael Burke, MD, STUDY_CHAIR, Medical College of Wisconsin

    Study Record Dates

    2027-01