Patient Derived Preclinical Models

Description

Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models. This study is being done to collect samples of tumor tissues, matched normal tissue when possible, and approximately 50 mL of blood.

Conditions

Cancer

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Study Overview

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Study Details

Study overview

Study goal is to collect tumor specimens that may inform cancer biology to eventually improve outcomes for patients with cancer. This proposal represents a highly collaborative effort to support cancer research with the goal of developing novel therapeutic strategies using patient derived preclinical models. This study is being done to collect samples of tumor tissues, matched normal tissue when possible, and approximately 50 mL of blood.

Patient Derived Preclinical Models

Patient Derived Preclinical Models

Condition
Cancer
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic in Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18 years of age and older
  • * Patient is a good medical candidate for a standard of care or research biopsy or surgical procedure to obtain tissue
  • * Uncontrolled concurrent illness including psychiatric illness, or situations that would limit compliance with the study requirements or the ability to willingly give written informed consent
  • * Institutionalized or incarcerated patients
  • * Inaccessible tumor for biopsy or patient does not have tumor tissue available for research use
  • * Biopsy must not be considered more than minimal risk to the patient.
  • * Have a contraindication to percutaneous biopsy including:
  • 1. Significant coagulopathy that cannot be adequately corrected.
  • 2. Severely compromised cardiopulmonary function or hemodynamic instability.
  • 3. Lack of a safe pathway to the lesion per the interventional radiologist.
  • 4. Inability of the patient to cooperate with, or to be positioned for, the procedure.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Aaron S. Mansfield, M.D., PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2028-03-31