RECRUITING

Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to assess feasibility, acceptability, and safety of providing transcranial direct current stimulation( tDCS) to Huntingtons Disease (HD) patients in the early to middle stages and to assess the efficacy of tDCS for HD-related behavioral, cognitive and other symptoms

Official Title

Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease

Quick Facts

Study Start:2023-06-21
Study Completion:2024-05-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05326451

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * confirmed HD mutation carriers
  2. * early (stages 1 and 2) or moderate (stage 3) stages according to Shoulson-Fahn
  3. * exhibit mild to moderate behavioral symptoms, such as clinically diagnosed apathy, irritability, anxiety, depression, aggression and repetition
  4. * stable doses of medications for at least one month
  1. * unstable medical conditions
  2. * history of epilepsy
  3. * metallic objects in the brain
  4. * clinical diagnosis of major cognitive disorder or dementia
  5. * Have risk of suicidal behavior, defined as any suicidal behavior or suicidal ideation of type 4

Contacts and Locations

Study Contact

Erin Stimming, MD
CONTACT
(713) 500-7033
Erin.E.Furr@uth.tmc.edu
Thiago Macedo e Cordeiro, MD
CONTACT
(713) 486-2559
Thiago.MacedoeCordeiro@uth.tmc.edu

Principal Investigator

Erin Stimming, MD
PRINCIPAL_INVESTIGATOR
The University of Texas Health Science Center, Houston

Study Locations (Sites)

The University of Texas Health Science Center at Houston
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: The University of Texas Health Science Center, Houston

  • Erin Stimming, MD, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center, Houston

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-06-21
Study Completion Date2024-05-01

Study Record Updates

Study Start Date2023-06-21
Study Completion Date2024-05-01

Terms related to this study

Keywords Provided by Researchers

  • transcranial direct current stimulation

Additional Relevant MeSH Terms

  • Huntington Disease