RECRUITING

Congenital Athymia Patient Registry

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This Congenital Athymia Patient Registry is an observational exposure-based registry study. It uses a prospective cohort design to follow patients who have been treated with RETHYMIC. Clinical studies conducted with investigational RETHYMIC showed that treatment can result in immune reconstitution and prolong life. This treatment-based registry is being conducted to learn more about the reconstitution process following treatment and the impact of treatment on longer-term survival and the occurrence of adverse events of special interest (AESI).

Official Title

Congenital Athymia Patient Registry of RETHYMIC

Quick Facts

Study Start:2022-05-25
Study Completion:2026-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05329935

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:0 Years to 21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Pediatric patients diagnosed with Congenital Athymia:
  2. * Who are scheduled for implantation with RETHYMIC within the next 30 days, or who were treated with RETHYMIC within the previous 60 days.
  3. * Who have provided written informed consent directly, or written informed consent has been provided by the patient, the parent, or legal guardian.
  1. * Written informed consent cannot be obtained.

Contacts and Locations

Study Contact

John Sleasman, M.D.
CONTACT
919-684-9914
john.sleasman@duke.edu

Study Locations (Sites)

Duke University School of Medicine
Durham, North Carolina, 27710
United States

Collaborators and Investigators

Sponsor: Sumitomo Pharma Switzerland GmbH

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-05-25
Study Completion Date2026-04

Study Record Updates

Study Start Date2022-05-25
Study Completion Date2026-04

Terms related to this study

Keywords Provided by Researchers

  • Congenital Athymia

Additional Relevant MeSH Terms

  • Complete DiGeorge Anomaly
  • Complete DiGeorge Syndrome
  • Congenital Athymia