Optoacoustic Detection of Inflammation Using MSOT Device

Description

The purpose of this study is to evaluate the safety and potential of a new experimental imaging instrument called multispectral optoacoustic tomography (MSOT) to detect inflammation in patients with chronic graft versus host disease of the skin or GI tract, Crohn's disease, or Colitis disease.

Conditions

Graft Vs Host Disease, Colitis, Crohn Disease

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Study Overview

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Study Details

Study overview

The purpose of this study is to evaluate the safety and potential of a new experimental imaging instrument called multispectral optoacoustic tomography (MSOT) to detect inflammation in patients with chronic graft versus host disease of the skin or GI tract, Crohn's disease, or Colitis disease.

Optoacoustic Detection of Inflammation Using Multispectral Optoacoustic Tomography

Optoacoustic Detection of Inflammation Using MSOT Device

Condition
Graft Vs Host Disease
Intervention / Treatment

-

Contacts and Locations

Oklahoma City

OU Health Stephenson Cancer Center, Oklahoma City, Oklahoma, United States, 73014

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients documented clinical/pathologic 1) acute or chronic colon or skin GVHD, 2) Crohn's disease, or 3) colitis
  • * Have acceptable hematologic status \[total hemoglobin (tHb) ≥ 7.0 mg/dL\]
  • * Patients ≥ 18 yrs of age
  • * Willing to comply with study procedures and be available for the duration of the study
  • * Patient has ability to understand and the willingness to provide a signed and dated IRB-approved informed consent document.
  • * Patients with a tattoo over the area of inflammation
  • * Pregnant patients are not eligible for this trial. Eligible patients (if applicable) will be required to document the date of the first day of their last menstrual cycle, and provide a negative pregnancy test if sexually active and of childbearing potential
  • * Patients who are breastfeeding
  • * Any open wound (skin ulcerations or infections) at or near the site of imaging that would preclude MSOT imaging.
  • * Any febrile illness that precludes or delays participation preoperatively

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Oklahoma,

Lacey McNally, PhD, PRINCIPAL_INVESTIGATOR, University of Oklahoma

Study Record Dates

2024-12-31