Individualizing Corticosteroid Use in Pneumonia

Description

In this study, researchers propose a unique (individualized) approach to steroid treatment seeking to give the right dose of steroid to the right patient and at the right time. This study seeks to compare usual care to an individualized steroid dosing strategy by testing a marker of inflammation in the blood called C- reactive protein (CRP). The overall goal is to reduce an individual's exposure to steroids and the risk of potential side effects thereby increasing the potential benefit of using steroids to control inflammation in pneumonia.

Conditions

Pneumonia

Study Overview

Study Details

Study overview

In this study, researchers propose a unique (individualized) approach to steroid treatment seeking to give the right dose of steroid to the right patient and at the right time. This study seeks to compare usual care to an individualized steroid dosing strategy by testing a marker of inflammation in the blood called C- reactive protein (CRP). The overall goal is to reduce an individual's exposure to steroids and the risk of potential side effects thereby increasing the potential benefit of using steroids to control inflammation in pneumonia.

Individualizing Corticosteroid Use in Pneumonia

Individualizing Corticosteroid Use in Pneumonia

Condition
Pneumonia
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Hospitalized adult (≥ 18 years) patients.
  • * Community acquired pneumonia.
  • * Contraindications or unwillingness to use corticosteroids by patient or provider.
  • * History of adrenal insufficiency, septic shock, or another absolute indication for steroid use.
  • * Suspected pulmonary vasculitis or other autoimmune pulmonary disorder.
  • * Positive pregnancy test
  • * Comfort care.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Yewande Odeyemi, MBBS, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2027-12