RECRUITING

Reducing Pain From Wisdom Molar Extractions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried for pain experience and pain medications taken during the first post-operative week and will present for a follow-up visit on Day 8.

Official Title

Non-randomized Prospective Pilot Study on Effect of Temporo-masseteric Nerve Block (TMNB) on Pain Reduction Following Wisdom Molar Extractions

Quick Facts

Study Start:2022-09-13
Study Completion:2025-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05335070

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 64 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18 years of age or older (up to 64 years)
  2. * Any demographic
  3. * ASA 1 and 2 (mild or absent systemic illnesses, deemed fit for undergoing dental extractions under intravenous sedation)
  4. * Not pregnant (as will not qualify to undergo procedure under intravenous sedation as part of routine standard-of-care)
  5. * Adequate mental ability to understand and provide informed consent
  6. * Has smart phone and internet connection
  1. * Age older than 64 years (because they are poor candidates for undergoing procedures under intravenous sedation)
  2. * Pregnant
  3. * Incapable of providing informed consent
  4. * Any systemic condition that renders the patient at higher risk for complications under intravenous sedation
  5. * Documented allergy to the dental local anesthetic
  6. * Inability to tolerate any of the commonly used pain medications such as combination opioids, acetaminophen (Tylenol®) or ibuprofen (Motrin® or Advil®)
  7. * Limitation in adequate mouth opening in presence/absence of pain

Contacts and Locations

Study Contact

Gayathri Subramanian, PhD, DMD
CONTACT
9739723418
subramga@sdm.rutgers.edu
Samuel YP Quek, DMD, MPH
CONTACT
732 570 1996

Principal Investigator

Gayathri D Subramanian, PhD, DMD
PRINCIPAL_INVESTIGATOR
Rutgers School of Dental Medicine

Study Locations (Sites)

The University Hospital- Dental Clinic
Newark, New Jersey, 07103
United States

Collaborators and Investigators

Sponsor: Rutgers, The State University of New Jersey

  • Gayathri D Subramanian, PhD, DMD, PRINCIPAL_INVESTIGATOR, Rutgers School of Dental Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-09-13
Study Completion Date2025-01

Study Record Updates

Study Start Date2022-09-13
Study Completion Date2025-01

Terms related to this study

Keywords Provided by Researchers

  • Temporo-masseteric Nerve Block
  • Twin Block
  • Prescription opioids
  • Acute Post-extraction pain

Additional Relevant MeSH Terms

  • Acute Pain