KM3D Multicenter Cancer Consortium: Predicting Patient Response Using 3D Cell Culture Models

Description

This study will assess the ability of the Known Medicine platform to predict the efficacy of certain cancer drug treatments and to validate that tumor organoid drug sensitivity is representative of patient treatment outcomes.

Conditions

Cancer, Predictive Cancer Model, Effects of Chemotherapy

Talk to us

Study Overview

On this page

Study Details

Study overview

This study will assess the ability of the Known Medicine platform to predict the efficacy of certain cancer drug treatments and to validate that tumor organoid drug sensitivity is representative of patient treatment outcomes.

KM3D Multicenter Cancer Consortium Study: Validation of In Vitro 3D Cell Culture Models for Tumor Drug Sensitivity After Tissue Removal

KM3D Multicenter Cancer Consortium: Predicting Patient Response Using 3D Cell Culture Models

Condition
Cancer
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic, Rochester, Minnesota, United States, 55905

Durham

Duke Cancer Institute, Durham, North Carolina, United States, 27710

Houston

MD Anderson Cancer Center, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * A demonstrated primary solid cancer for which it is medically indicated and planned to be surgically resected, biopsied, or drained (via malignant pleural effusion).
  • * The ability to ship the tissue sample within 24 hours of removal from the patient.
  • * Signed and dated consent to giving tissue as well as allowing for de-identified medical history information regarding administered treatments and treatment outcomes to be shared.
  • * over 18 years of age
  • * Presence of a condition(s) or diagnosis, either physical or psychological, or physical exam finding that precludes participation in the opinion of the Investigator.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Known Medicine, Inc.,

Andrea Mazzocchi, PhD, PRINCIPAL_INVESTIGATOR, Known Medicine, Inc.

Study Record Dates

2026-01-31