Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

Description

The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).

Conditions

Anesthesia, Propofol Adverse Reaction, Etomidate Adverse Reaction, Anesthesia Complication, Anesthesia; Adverse Effect, Anesthesia; Reaction

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Study Details

Study overview

The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7), and one using an admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), for anesthesia during endoscopic procedures at the Clements University Hospital (CUH) endoscopy lab (Endo).

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

Condition
Anesthesia
Intervention / Treatment

-

Contacts and Locations

Dallas

Clements University Hospital, Dallas, Texas, United States, 75390

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Adult patients (age ≥18 years old)
  • 2. Having endoscopic procedure at CUH with anesthesia
  • 3. ASA 3 or above
  • 4. Ejection Fraction test result available
  • 1. Known allergies or adverse reactions to study drugs or study drug components or preservatives
  • 2. Patient refusal
  • 3. Clinician refusal
  • 4. Documented cognitive impairments precluding subject ability to consent for themselves unless a surrogate documented legally acceptable decision maker consents for patient participation
  • 5. Prisoner or incarcerated or patients held by law enforcement officials in custody
  • 6. Pregnancy or patient refusal for pregnancy testing or screening (standard UTSW policy and protocol requires pregnancy testing for appropriate patients prior to anesthesia)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Texas Southwestern Medical Center,

Kapil Anand, STUDY_DIRECTOR, University of Texas

Study Record Dates

2024-12