RECRUITING

The Dynamics of Human Atrial Fibrillation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Atrial fibrillation (AF) is an enormous public health problem in the United States, affecting 2-5 million Americans and causing rapid heart beats, stroke, heart failure or death. In this project, the applicant will develop a novel framework to better understand human AF that builds on agreement between several concepts for the disease. The applicant will develop strategies to identify AF patients who will best respond to each of several therapies, to guide personalized therapy.

Official Title

The Dynamics of Human Atrial Fibrillation

Quick Facts

Study Start:2020-08-18
Study Completion:2026-12-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05366361

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:22 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * referred for ablation or Maze surgery at Stanford Medicine for persistent AF (i.e. which requires cardioversion to terminate and/or lasts \>7 days)
  2. * Per our clinical practice and guidelines (Calkins et al., Heart Rhythm 2018), patients will have failed or be intolerant of \>or= 1 anti-arrhythmic drug. Patients after Maze surgery typically have failed prior endocardial ablation.
  1. * active coronary ischemia or decompensated heart failure
  2. * atrial or ventricular clot on trans-esophageal echocardiography
  3. * pregnancy (to minimize fluoroscopic exposure)
  4. * inability or unwillingness to provide informed consent
  5. * rheumatic valve disease (results in a unique AF phenotype)
  6. * thrombotic disease or venous filters
  7. * prior chest surgery is a relative contraindication for Maze surgery

Contacts and Locations

Study Contact

Sanjiv Narayan, MD
CONTACT
(650) 724-1850
sanjiv1@stanford.edu
Kathleen Mills, BA
CONTACT
kmills2@stanford.edu

Study Locations (Sites)

Stanford University
Stanford, California, 94305
United States

Collaborators and Investigators

Sponsor: Stanford University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-08-18
Study Completion Date2026-12-30

Study Record Updates

Study Start Date2020-08-18
Study Completion Date2026-12-30

Terms related to this study

Keywords Provided by Researchers

  • ablation
  • arrhythmias, cardiac
  • atrial fibrillation

Additional Relevant MeSH Terms

  • Atrial Fibrillation
  • Arrhythmias, Cardiac