South Asians and Coronary Plaque Registry

Description

Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The registry will serve to generate primary observations as well as preliminary data for future studies.

Conditions

Coronary Artery Disease, Heart Diseases

Study Overview

Study Details

Study overview

Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The registry will serve to generate primary observations as well as preliminary data for future studies.

South Asians and Coronary Plaque Registry

South Asians and Coronary Plaque Registry

Condition
Coronary Artery Disease
Intervention / Treatment

-

Contacts and Locations

Dallas

University of Texas Southwestern Medical Center, Dallas, Texas, United States, 75390

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Males and Females: Age 18 years or above
  • * South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh)
  • * We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers)
  • * Sampling Method: Probability Sample
  • * Under the age of 18 years
  • * Unable to give informed consent
  • * Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min
  • * Baseline heart rate≥70 bpm or ≥66 bpm after beta blocker
  • * Body mass index (BMI) of 35 or greater
  • * Prior anaphylactic/non-anaphylactic reaction or other contraindication to iodinated contrast
  • * Anyone who cannot do CCTA for any reason
  • * Pregnancy

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Texas Southwestern Medical Center,

Anand Rohatgi, MD, PRINCIPAL_INVESTIGATOR, UT Southwestern Medical Center

Study Record Dates

2027-04-30