RECRUITING

South Asians and Coronary Plaque Registry

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The registry will serve to generate primary observations as well as preliminary data for future studies.

Official Title

South Asians and Coronary Plaque Registry

Quick Facts

Study Start:2022-06-15
Study Completion:2027-04-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05367297

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Males and Females: Age 18 years or above
  2. * South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh)
  3. * We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers)
  4. * Sampling Method: Probability Sample
  1. * Under the age of 18 years
  2. * Unable to give informed consent
  3. * Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min
  4. * Baseline heart rate≥70 bpm or ≥66 bpm after beta blocker
  5. * Body mass index (BMI) of 35 or greater
  6. * Prior anaphylactic/non-anaphylactic reaction or other contraindication to iodinated contrast
  7. * Anyone who cannot do CCTA for any reason
  8. * Pregnancy

Contacts and Locations

Study Contact

Shailesh Jaiswal
CONTACT
214.648.2872
SAHealth@UTSouthwestern.edu
Anand Rohatgi
CONTACT
214.645.7500
SAHealth@UTSouthwestern.edu

Principal Investigator

Anand Rohatgi, MD
PRINCIPAL_INVESTIGATOR
UT Southwestern Medical Center

Study Locations (Sites)

University of Texas Southwestern Medical Center
Dallas, Texas, 75390
United States

Collaborators and Investigators

Sponsor: University of Texas Southwestern Medical Center

  • Anand Rohatgi, MD, PRINCIPAL_INVESTIGATOR, UT Southwestern Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-06-15
Study Completion Date2027-04-30

Study Record Updates

Study Start Date2022-06-15
Study Completion Date2027-04-30

Terms related to this study

Additional Relevant MeSH Terms

  • Coronary Artery Disease
  • Heart Diseases