RECRUITING

Tennessee Alzheimer's Project

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary objective of the Vanderbilt Alzheimer's Disease Research Center (VADRC) is to provide local and national researchers with access to a well-characterized and diverse clinical cohort, including participant referrals, biosamples, clinical data, and neuroimaging data. The VADRC Clinical Core will create an infrastructure to support research efforts of both local and national investigator studies to develop early detection, prevention, and treatment strategies for Alzheimer's disease. The Clinical Core intends to enroll up to 1000 participants, including individuals who are cognitively unimpaired, have mild cognitive impairment, or have Alzheimer's disease. This cohort of about 1000 participants will be called the Tennessee Alzheimer's Project. Participants will be seen annually for comprehensive clinical characterization and then referred to other studies to enhance Alzheimer's disease research activities.

Official Title

Tennessee Alzheimer's Project

Quick Facts

Study Start:2021-10-27
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05372172

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 60 or older
  2. * Meet standard criteria for (a) cognitively unimpaired, (b) mild cognitive impairment, or (c) Alzheimer's disease
  3. * English speaking
  4. * Individuals who lack decisional capacity to provide informed consent at baseline will not be enrolled in the study
  1. * No available reliable study partner (reliable is defined as someone who interacts significantly with the participant and is available to participate in study visits in person or by phone)
  2. * History of major psychiatric illness (e.g., schizophrenia, bipolar), neurological illness (e.g., epilepsy, multiple sclerosis, Parkinson's disease), or head injury with significant loss of consciousness.
  3. * Unable to undergo MRI (e.g., claustrophobia, ferrous metal in body)

Contacts and Locations

Study Contact

Michelle Houston
CONTACT
615-875-3175
michelle.houston@vumc.org

Principal Investigator

Angela Jefferson, PhD
PRINCIPAL_INVESTIGATOR
Professor of Neurology

Study Locations (Sites)

Vanderbilt University Medical Center
Nashville, Tennessee, 37232
United States

Collaborators and Investigators

Sponsor: Vanderbilt University Medical Center

  • Angela Jefferson, PhD, PRINCIPAL_INVESTIGATOR, Professor of Neurology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-10-27
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2021-10-27
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Alzheimer's disease
  • biomarkers
  • brain MRI
  • mild cognitive impairment
  • vascular risk factors
  • longitudinal studies

Additional Relevant MeSH Terms

  • Aging
  • Alzheimer Disease
  • Biomarker
  • Cognitive Dysfunction
  • Mild Cognitive Impairment
  • Dementia
  • Cognition