RECRUITING

Exercise Capacity Before and After AF Ablation in Patients With HFpEF

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

In a prospective, observational pilot study of patients scheduled for an atrial fibrillation (AF) ablation at the University of Vermont Medical Center the investigators will compare exercise capacity before and four months after AF ablation.

Official Title

Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction Before and After Ablation of Atrial Fibrillation

Quick Facts

Study Start:2022-04-15
Study Completion:2024-12-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05376748

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 110 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * H2FpEF score of ≥ 6 (corresponding to \>90% probability of HFpEF (19))
  2. * echocardiogram within the past 2 years that reported a LV ejection fraction ≥ 50%
  3. * at least one symptom of HF (dyspnea on exertion, orthopnea or paroxysmal nocturnal dyspnea).
  4. * AF ablation scheduled at UVMMC
  1. * Life expectancy \<12 months
  2. * moderate or more valvular disease
  3. * inability to walk on a treadmill

Contacts and Locations

Study Contact

Nicole Habel, MD
CONTACT
8028470000
nicole.habel@uvmhealth.org
Amy Henderson
CONTACT
amy.henderson@uvmhealth.org

Principal Investigator

Nicole Habel, MD
PRINCIPAL_INVESTIGATOR
University of Vermont

Study Locations (Sites)

University of Vermont Medical Center
Burlington, Vermont, 05405
United States

Collaborators and Investigators

Sponsor: University of Vermont

  • Nicole Habel, MD, PRINCIPAL_INVESTIGATOR, University of Vermont

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-15
Study Completion Date2024-12-30

Study Record Updates

Study Start Date2022-04-15
Study Completion Date2024-12-30

Terms related to this study

Keywords Provided by Researchers

  • Ablation
  • HFpEF
  • atrial fibrillation
  • exercise capacity
  • peak oxygen consumption

Additional Relevant MeSH Terms

  • Heart Failure With Preserved Ejection Fraction
  • Atrial Fibrillation