RECRUITING

Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

One of the most challenging tasks for blind and visually impaired individuals is navigation through a complex environment. The goal of the present multidisciplinary study is to increase spatial-cognition abilities in people who are blind or visually impaired through training with the previously-developed Cognitive-Kinesthetic Rehabilitation Training to improve navigation, and to investigate the resultant neuroplastic brain reorganization through multimodal brain imaging. In accordance with National Eye Institute (NEI) strategic goals, this multidisciplinary project will promote the development of well-informed new approaches to navigational rehabilitation, memory enhancement and cross-modal brain plasticity to benefit 'cutting edge' fields of mobile assistive technologies, vision restoration and memory facilitation for the aging brain.

Official Title

Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment

Quick Facts

Study Start:2022-02-15
Study Completion:2024-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05377853

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Vision from \< 20/500 to NLP (No Light Perception)
  2. * Vision from \< 20/500 to NLP
  3. * Within average gender range for height +/-1 standard deviation
  4. * Within average gender range for weight +/-1 standard deviation
  5. * Comfortable with MRI procedures
  1. * Neurological deficits
  2. * Inability to normally control lower or upper extremities
  3. * Inability to hear and understand instructions.
  4. * All standard MRI exclusion criteria, such as having any metallic objects in the body, or being too large to fit or operate comfortably in the scanner bore.

Contacts and Locations

Study Contact

Lora T Likova
CONTACT
415 345 2066
lora@ski.org
Christopher W Tyler
CONTACT
415 345 2020
cwt@ski.org

Principal Investigator

Lora T Likova
PRINCIPAL_INVESTIGATOR
Senior Scientist

Study Locations (Sites)

Smith-Kettlewell Eye Research Institute
San Francisco, California, 94115
United States

Collaborators and Investigators

Sponsor: Smith-Kettlewell Eye Research Institute

  • Lora T Likova, PRINCIPAL_INVESTIGATOR, Senior Scientist

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-02-15
Study Completion Date2024-02

Study Record Updates

Study Start Date2022-02-15
Study Completion Date2024-02

Terms related to this study

Keywords Provided by Researchers

  • blindness
  • plasticity
  • spatial memory
  • training
  • navigation

Additional Relevant MeSH Terms

  • Blindness
  • Blindness, Acquired
  • Low Vision
  • Blindness, Complete