The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

Description

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

Conditions

Ventilatory Depression, Postoperative Respiratory Failure

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Study Overview

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Study Details

Study overview

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

Recovery of Ventilation After General Anesthesia for Robotic-Assisted Laparoscopic Nephrectomy or Prostatectomy: The Effect of Oxygen Supplementation

The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

Condition
Ventilatory Depression
Intervention / Treatment

-

Contacts and Locations

Stanford

Stanford University School of Medicine, Stanford, California, United States, 94305

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * American Society of Anesthesiologists (ASA) physical status I-III
  • * Body mass index (BMI) less than 40 kg/m2
  • * Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy or prostatectomy.
  • * Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder
  • * Chronic pain condition that is being treated with opioids
  • * Patients with a hematocrit lower than 30% at the end of surgery, or those with an excessive blood loss, requiring transfusion of blood products during surgery.

Ages Eligible for Study

18 Years to 70 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Stanford University,

Anthony Doufas, MD, PhD, PRINCIPAL_INVESTIGATOR, Professor, Department of Anesthesiology, Stanford University Medical School

Study Record Dates

2025-12