RECRUITING

Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this collaborative CTSA (Clinical and Translational Science Award) application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in breastfeeding mothers and their infants

Official Title

Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

Quick Facts

Study Start:2022-12-05
Study Completion:2026-10-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05380531

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. 1. Health conditions including uncontrolled diabetes (gestational or pre-existing) or hypertension (pre-eclampsia, eclampsia, or chronic)
  2. 2. Any history of opioid misuse before or during pregnancy-per self-report and clinical notes
  3. 3. Preoperative severe pain and opioid use/misuse, allergy to oxycodone
  4. 4. Allergy to oxycodone
  5. 5. Significant neurological disorders, liver and renal diseases

Contacts and Locations

Study Contact

Senthilkumar Sadhasivam, MD, MPH
CONTACT
4126472994
sadhasivams@upmc.edu
Carly Riedmann, MPH
CONTACT
412-623-4147
riedmannca@upmc.edu

Principal Investigator

Senthilkumar Sadhasivam, MD, MPH
PRINCIPAL_INVESTIGATOR
University of Pittsburgh

Study Locations (Sites)

UPMC Magee Women's Hospital
Pittsburgh, Pennsylvania, 15213
United States
University of Pittsburgh
Pittsburgh, Pennsylvania, 15260
United States

Collaborators and Investigators

Sponsor: Senthil Sadhasivam

  • Senthilkumar Sadhasivam, MD, MPH, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-12-05
Study Completion Date2026-10-30

Study Record Updates

Study Start Date2022-12-05
Study Completion Date2026-10-30

Terms related to this study

Keywords Provided by Researchers

  • Opioid Exposure

Additional Relevant MeSH Terms

  • Cesarean Section Complications
  • Opioid Use